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QuickView for DPP4 (gene)


Gene Symbol:
DPP4 Homo sapiens Homo sapiens
Full name:
dipeptidyl peptidase 4
Synonyms:
ADABP, ADCP2, CD26, DPPIV, TP103, dipeptidyl peptidase 4, ADCP-2, DPP IV, T-cell activation antigen CD26, adenosine deaminase complexing protein 2, dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
Genomic Location:
Chr 2: 162557001-162639298
Description:
The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2q24.2


Transcripts Names
NM_001935
XM_005246371
Protein Names
P27487
Q53TN1



GO Molecular Function

enzyme binding | signaling receptor binding | hydrolase activity | catalytic activity | serine hydrolase activity | exopeptidase activity | identical protein binding | protein binding | protein homodimerization activity | aminopeptidase activity | dipeptidyl-peptidase activity | protein dimerization activity | virus receptor activity | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | protease binding | peptidase activity

GO Biological Process

cell motility | behavioral fear response | proteolysis | regulation of localization | regulation of immune system process | negative regulation of cellular process | positive regulation of lymphocyte activation | defense response | lymphocyte costimulation | regulation of extracellular matrix organization | epithelial cell migration | positive regulation of cell adhesion | regulation of peptide hormone secretion | cellular process | localization | exploration behavior | epithelium migration | response to hypoxia | interspecies interaction between organisms | regulation of cellular process | leukocyte activation | motor behavior | entry into host cell | viral life cycle | T cell activation | regulation of peptide secretion | response to stimulus | regulation of extracellular matrix disassembly | regulation of insulin secretion | negative regulation of extracellular matrix organization | positive regulation of immune system process | response to stress | endothelial cell migration | regulation of cell proliferation | psychomotor behavior | positive regulation of cell-cell adhesion | positive regulation of cell activation | positive regulation of T cell activation | regulation of protein transport | regulation of peptide transport | regulation of cell adhesion | locomotion | response to oxygen levels | nitrogen compound metabolic process | cell migration | regulation of hormone levels | regulation of hormone secretion | regulation of T cell activation | viral entry into host cell | exopeptidase activity | regulation of lymphocyte activation | locomotory behavior | regulation of cell adhesion mediated by integrin | positive regulation of cell proliferation | viral process | regulation of cell-cell adhesion mediated by integrin | lymphocyte activation | aminopeptidase activity | multicellular organismal response to stress | fear response | protein metabolic process | regulation of establishment of protein localization | dipeptidyl-peptidase activity | metabolic process | negative regulation of extracellular matrix disassembly | positive regulation of leukocyte activation | regulation of secretion | behavior | cell adhesion | organic substance metabolic process | virus receptor activity | regulation of cell activation | regulation of protein secretion | serine-type endopeptidase activity | serine-type peptidase activity | cell activation | T cell costimulation | regulation of cell communication | endopeptidase activity | behavioral defense response | regulation of transport | regulation of cell-cell adhesion | locomotory exploration behavior | immune system process | peptidase activity | ameboidal-type cell migration | regulation of protein localization | positive regulation of leukocyte cell-cell adhesion | regulation of cellular component organization | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | apical plasma membrane | adherens junction | organelle membrane | cell projection membrane | focal adhesion | cytoplasmic vesicle | cell | intrinsic component of membrane | lamellipodium | cytoplasm | intercellular canaliculus | cell-substrate junction | intracellular organelle | membrane microdomain | leading edge membrane | apical part of cell | cell-cell junction | cell projection | plasma membrane | cell leading edge | membrane raft | vacuole | vesicle | extracellular exosome | invadopodium membrane | lytic vacuole | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | lysosome | extracellular space | cell periphery | cell-substrate adherens junction | invadopodium | intracellular vesicle | cell surface | endocytic vesicle | intracellular | cell junction | lysosomal membrane | membrane | lamellipodium membrane | vacuolar membrane