QuickView for DPP8 (gene)

Gene Symbol:

DPP8 Homo sapiens

Full name:

dipeptidyl peptidase 8

Synonyms:

DP8, DPRP-1, DPRP1, MST097, MSTP097, MSTP135, MSTP141, dipeptidyl peptidase 8, DPP VIII, dipeptidyl peptidase IV-related protein 1, dipeptidyl peptidase VIII, prolyl dipeptidase DPP8

Genomic Location:

Chr 15: 63525051-63597088

Description:

This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl pep...

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This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GABP_B ,  PU1_Q6 ,  CATRRAGC_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  NERF_Q2 ,  MGGAAGTG_GABP_B ,  CETS1P54_01 ,  ELK1_01 ,  SCGGAAGY_ELK1_02 ,  RGAGGAARY_PU1_Q6 ,  NRF2_01 ,  ELK1_02 ,  ELF1_Q6

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Cytogenetic Map:

15q22.31

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