QuickView for DRAP1;jsessionid=AB906B5F2D86D41EAD484CA1FBCE3C5D (gene)
- Gene Symbol:
- DRAP1
Homo sapiens - Full name:
- DR1 associated protein 1
- Synonyms:
- NC2-alpha, dr1-associated corepressor, negative co-factor 2-alpha, negative cofactor 2 alpha
- Genomic Location:
- Chr 11: 65443304-65445607
- Description:
-
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFI...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
11q13.1
GO Molecular Function
transcription factor activity, transcription factor binding | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | core promoter binding | transcription factor activity, RNA polymerase II transcription factor binding | nucleic acid binding | chromatin binding | DNA binding | transcription corepressor activity | RNA polymerase II transcription factor activity, TBP-class protein binding | identical protein binding | protein heterodimerization activity | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | organic cyclic compound binding | transcription coactivator activity | protein binding | DNA-binding transcription factor activity | transcription factor binding | protein dimerization activity | transcription coregulator activity | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | cellular nitrogen compound biosynthetic process | protein-DNA complex assembly | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | transcription corepressor activity | RNA polymerase II transcription factor activity, TBP-class protein binding | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | DNA-templated transcriptional preinitiation complex assembly | RNA polymerase II transcriptional preinitiation complex assembly | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | protein-containing complex assembly | DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | positive regulation of metabolic process | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
