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QuickView for DSPP (gene)


Gene Symbol:
DSPP Homo sapiens Homo sapiens
Full name:
dentin sialophosphoprotein
Synonyms:
DFNA39, DGI1, DMP3, DPP, DSP, dentin sialophosphoprotein, dentin phosphophoryn, dentin phosphoprotein, dentin phosphoryn, dentin sialoprotein
Genomic Location:
Chr 4: 88748705-88757049
Description:
This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein p...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Bos taurus Danio rerio Canis lupus familiaris Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4q22.1


Transcripts Names
NM_014208
Protein Names
Q9NZW4
A8MUI0
O95815



GO Molecular Function

structural molecule activity | cation binding | protein-containing complex binding | collagen binding | ion binding | protein binding | calcium ion binding | metal ion binding | extracellular matrix structural constituent

GO Biological Process

response to extracellular stimulus | molting cycle | regulation of odontoblast differentiation | extracellular structure organization | response to hormone | positive regulation of enamel mineralization | positive regulation of developmental process | response to dexamethasone | cell differentiation | cellular response to extracellular stimulus | response to drug | positive regulation of biomineral tissue development | cellular process | odontogenesis | response to hypoxia | response to growth factor | tissue development | regulation of cell differentiation | regulation of cellular process | cellular response to lipid | regulation of odontogenesis of dentin-containing tooth | epithelium development | cellular component organization | response to transforming growth factor beta | response to stimulus | cellular response to xenobiotic stimulus | response to stress | regulation of epithelial cell differentiation | hair follicle maturation | extracellular matrix organization | cellular response to organic cyclic compound | regulation of odontogenesis | cartilage development | cellular response to hormone stimulus | system development | response to oxygen levels | multicellular organism development | neuroepithelial cell differentiation | response to ketone | response to lipid | animal organ morphogenesis | response to corticosteroid | dentinogenesis | cellular response to glucocorticoid stimulus | positive regulation of odontogenesis | epidermis development | skin development | response to xenobiotic stimulus | cellular response to corticosteroid stimulus | cellular response to drug | cell communication | odontogenesis of dentin-containing tooth | regulation of enamel mineralization | hair cycle | response to organic substance | response to antineoplastic agent | response to mechanical stimulus | regulation of animal organ morphogenesis | anatomical structure development | developmental maturation | hair cycle process | connective tissue development | animal organ development | odontoblast differentiation | skin epidermis development | biomineral tissue development | cellular response to steroid hormone stimulus | positive regulation of odontogenesis of dentin-containing tooth | cellular response to dexamethasone stimulus | anatomical structure formation involved in morphogenesis | response to organic cyclic compound | anatomical structure morphogenesis | regulation of developmental process | developmental process | cellular response to cell-matrix adhesion | epithelial cell differentiation | ossification | skeletal system development | cellular response to organic substance | response to carbohydrate | response to steroid hormone | hair follicle development | response to glucocorticoid | positive regulation of tooth mineralization | multicellular organismal process

GO Cellular Component

extracellular matrix | cell | cytoplasm | extracellular region | intracellular