QuickView for Dab1 (gene)

Gene Symbol:

DAB1 Homo sapiens

Full name:

DAB1, reelin adaptor protein

Synonyms:

SCA37, disabled homolog 1, Dab reelin signal transducer 1, Dab, reelin signal transducer, homolog 1

Genomic Location:

Chr 1: 57236167-58488799

Description:

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein enco...

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The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SMTTTTGT_UNKNOWN ,  GATA3_01 ,  AML_Q6 ,  NKX3A_01 ,  AAANWWTGC_UNKNOWN ,  AP2GAMMA_01 ,  SRY_01 ,  PBX1_01 ,  MYAATNNNNNNNGGC_UNKNOWN ,  AML1_01 ,  CEBPDELTA_Q6 ,  TEF1_Q6 ,  NKX62_Q2 ,  RRAGTTGT_UNKNOWN ,  OCT1_03 ,  CCCNNGGGAR_OLF1_01 ,  NKX25_02 ,  GCCNNNWTAAR_UNKNOWN ,  GATA1_02 ,  RNGTGGGC_UNKNOWN ,  AML1_Q6 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  ZIC2_01 ,  CTGCAGY_UNKNOWN ,  E2F_Q2 ,  AACTTT_UNKNOWN ,  CP2_01

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Cytogenetic Map:

1p32.2

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