QuickView for Dazl;jsessionid=FE7F23275725084B99937659020D2231;jsessionid=A52CD6C832BF68B366F4BBDE9B9EE618 (gene)

Gene Symbol:

Dazl Mus musculus

Full name:

deleted in azoospermia-like

Synonyms:

Daz-like, Dazh, Dazl1, Dazla, Tpx-2, Tpx2, deleted in azoospermia-like, DAZ-like autosomal, deleted in azoospermia-like 1

Genomic Location:

Chr 17: 50418726-50432924

Description:

This gene encodes a member of the depleted in azoospermia-like (DAZL) protein family. Members of this family contain an RNA recognition motif, interact with poly A binding proteins, and may be involved in the initiation of translation. The encoded protein is expressed in the cytoplasm of pluripotent stem cells, and in both male and female germ cell...

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This gene encodes a member of the depleted in azoospermia-like (DAZL) protein family. Members of this family contain an RNA recognition motif, interact with poly A binding proteins, and may be involved in the initiation of translation. The encoded protein is expressed in the cytoplasm of pluripotent stem cells, and in both male and female germ cells, where it is essential for gametogenesis. Disruption of this gene is associated with infertility. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MYCMAX_01 ,  HSF1_01 ,  HSF2_01 ,  USF_C ,  MYCMAX_B ,  PIT1_Q6 ,  AAACCAC_MIR140 ,  ATAAGCT_MIR21 ,  GTGCAAA_MIR507 ,  TTCYRGAA_UNKNOWN ,  WTTGKCTG_UNKNOWN ,  TTCNRGNNNNTTC_HSF_Q6 ,  RGAANNTTC_HSF1_01 ,  CACGTG_MYC_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-21 ,  Predicted Gene Targets for miR-378* ,  Predicted Gene Targets for miR-140 ,  Predicted Gene Targets for miR-363

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