Correlation Engine 2.0
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QuickView for Dcc (gene)

Gene Symbol:
DCC Homo sapiens Homo sapiens
Full name:
DCC netrin 1 receptor
CRC18, CRCR1, HGPPS2, IGDCC1, MRMV1, NTN1R1, netrin receptor DCC, colorectal cancer suppressor, deleted in colorectal carcinoma, immunoglobulin superfamily DCC subclass member 1, putative colorectal tumor suppressor, tumor suppressor protein DCC
Genomic Location:
Chr 18: 48120569-49311780
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate...
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 18

GO Molecular Function

transmembrane signaling receptor activity | signaling receptor activity | protein binding | netrin receptor activity

GO Biological Process

cell morphogenesis | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | negative regulation of netrin-activated signaling pathway | regulation of cell development | neuron migration | negative regulation of cellular process | cell differentiation | negative regulation of dendrite development | nervous system development | cell part morphogenesis | neurogenesis | generation of neurons | regulation of neuron death | cellular process | negative regulation of axonogenesis | central nervous system neuron axonogenesis | localization | cell projection morphogenesis | extrinsic apoptotic signaling pathway | negative regulation of signaling | neuron development | negative regulation of developmental growth | central nervous system neuron differentiation | axon guidance | regulation of neuron projection development | regulation of cell differentiation | regulation of cellular process | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | response to stimulus | cell morphogenesis involved in neuron differentiation | negative regulation of collateral sprouting | neuron projection guidance | negative regulation of neuron projection development | programmed cell death | regulation of cellular component size | locomotion | central nervous system neuron development | apoptotic process | system development | regulation of signal transduction | negative regulation of growth | central nervous system projection neuron axonogenesis | multicellular organism development | cell migration | regulation of axonogenesis | anterior/posterior axon guidance | regulation of neuron differentiation | axon development | dorsal/ventral axon guidance | axonogenesis | cell morphogenesis involved in differentiation | spinal cord ventral commissure morphogenesis | cell communication | negative regulation of cell growth | apoptotic signaling pathway | neuron differentiation | regulation of cell morphogenesis involved in differentiation | regulation of growth | negative regulation of cell projection organization | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | neuron projection development | cell death | animal organ development | negative regulation of neuron differentiation | regulation of dendrite development | regulation of collateral sprouting | regulation of cell communication | negative regulation of signal transduction | signaling | cell development | regulation of developmental growth | extrinsic apoptotic signaling pathway in absence of ligand | regulation of cell size | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | regulation of cell growth | netrin-activated signaling pathway | netrin receptor activity | central nervous system development | spinal cord development | regulation of cell projection organization | regulation of cell death | negative regulation of cell development | chemotaxis | negative regulation of cell differentiation | regulation of cellular component organization | signal transduction | regulation of signaling | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

integral component of membrane | neuron projection | cell | intrinsic component of membrane | cytoplasm | cell projection | plasma membrane | cell periphery | axon | cytosol | intracellular | membrane