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QuickView for Ddx4 (gene)


Gene Symbol:
DDX4 Homo sapiens Homo sapiens
Full name:
DEAD-box helicase 4
Synonyms:
VASA, probable ATP-dependent RNA helicase DDX4, DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, DEAD box protein 4, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4, vasa homolog
Genomic Location:
Chr 5: 55070533-55148362
Description:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patte...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5
5q11.2





GO Molecular Function

nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

RNA metabolic process | gene silencing by RNA | cell motility | DNA modification | negative regulation of cellular process | cell differentiation | male gamete generation | male meiotic nuclear division | flagellated sperm motility | cellular process | localization | regulation of transposition | multicellular organismal reproductive process | gamete generation | regulation of cellular process | gene silencing | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | male meiosis I | sperm motility | reproduction | cellular nitrogen compound metabolic process | negative regulation of metabolic process | macromolecule modification | locomotion | nitrogen compound metabolic process | reproductive process | multicellular organism development | negative regulation of transposition | piRNA biosynthetic process | regulation of gene expression | methylation | cell cycle | DNA methylation | piRNA metabolic process | multicellular organism reproduction | DNA metabolic process | anatomical structure development | nuclear division | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | meiosis I | meiotic cell cycle | developmental process | organelle organization | spermatogenesis | DNA methylation involved in gamete generation | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | sexual reproduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

pole plasm | cell | ribonucleoprotein granule | cytoplasm | P granule | intracellular organelle | germ plasm | protein-containing complex | ribonucleoprotein complex | piP-body | organelle | cytoplasmic ribonucleoprotein granule | intracellular | pi-body