QuickView for Destrin (gene)

Gene Symbol:

DSTN Homo sapiens

Full name:

destrin, actin depolymerizing factor

Synonyms:

ACTDP, ADF, HEL32, bA462D18.2, destrin, actin-depolymerizing factor, bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP)), epididymis luminal protein 32

Genomic Location:

Chr 20: 17498599-17536652

Description:

The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have be...

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The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  SMTTTTGT_UNKNOWN ,  PR_02 ,  TGANTCA_AP1_C ,  PR_01 ,  AAANWWTGC_UNKNOWN ,  AP1_Q6 ,  TATAAA_TATA_01 ,  CAGGTG_E12_Q6 ,  YY1_01 ,  AP1FJ_Q2 ,  AR_01 ,  SRF_Q4 ,  NFY_01 ,  AHR_Q5 ,  AP1_Q4 ,  AREB6_03 ,  FREAC2_01 ,  GR_01 ,  ARGGGTTAA_UNKNOWN ,  CTGCAGY_UNKNOWN ,  SRF_Q5_01 ,  AP1_Q2 ,  SRF_C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-495

Cytogenetic Map:

20p12.1

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