QuickView for Dicer (gene)

Gene Symbol:

DICER1 Homo sapiens

Full name:

dicer 1, ribonuclease III

Synonyms:

DCR1, Dicer, Dicer1e, HERNA, K12H4.8-LIKE, MNG1, RMSE2, endoribonuclease Dicer, Dicer1, Dcr-1 homolog, dicer 1, double-stranded RNA-specific endoribonuclease, dicer 1, ribonuclease type III, helicase MOI, helicase with RNAse motif

Genomic Location:

Chr 14: 94622319-94693512

Description:

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. A...

View Full Description

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  PAX4_04 ,  TTTGCAC_MIR19A_MIR19B ,  ACACTCC_MIR122A ,  GCATTTG_MIR105 ,  HOXA4_Q2 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  GCTTGAA_MIR498 ,  CAGGTA_AREB6_01 ,  CTCAGGG_MIR125B_MIR125A ,  TGCACTG_MIR148A_MIR152_MIR148B ,  ATACCTC_MIR202 ,  TGCCTTA_MIR124A ,  ATGCTGC_MIR103_MIR107 ,  ACTACCT_MIR196A_MIR196B ,  TGCTGAY_UNKNOWN ,  TAATAAT_MIR126 ,  POU1F1_Q6 ,  PTF1BETA_Q6 ,  MEIS1AHOXA9_01 ,  TTGTTT_FOXO4_01 ,  IRF7_01 ,  TGCTTTG_MIR330 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  TGACATY_UNKNOWN

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-122a ,  Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-196 ,  Predicted Gene Targets for miR-330 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-140 ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-495

View More

View Less

Cytogenetic Map:

14q32.13

search → result