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QuickView for Diphenylpyraline (compound)
PubChem
| Name: | diphenylpyraline |
|---|---|
| PubChem Compound ID: | 3103 |
| Molecular formula: | C19H23NO |
| Molecular weight: | 281.392 g/mol |
| Synonyms: |
Diphenylpyrilene; Neargal; AN 1041; NCGC00016395-01; Diphenpyraline hydrochloride; Dayfen; AIDS-033087; Histyn; Difenilpiralina [INN-Spanish]; KBio2_006618.
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DrugBank
Identification
| Name: | diphenylpyraline |
|---|---|
| Name (isomeric): | DB01146 |
| Drug Type: | small molecule |
| Synonyms: |
Diphenylpyrilene; Diphenylpyralamine; Diphenylpyraline Hydrochloride
|
| Brand: | Hystryl, Hispril, Allergen, Neargal, Lyssipoll, Dafen, Mepiben, Histryl, Histyn, Dayfen, Belfene, Diafen |
| Brand name mixture: | Creo-Rectal Enfant(Camphor + Diphenylpyraline Hydrochloride + Guaiacol Carbonate), Solucodan-H(Diphenylpyraline Hydrochloride + Hydrocodone Bitartrate + Menthol + Potassium Guaiacol Sulphonate + Sodium Citrate), Chemhisdex Dm Decongestant(Dextromethorphan Hydrobromide + Diphenylpyraline Hydrochloride + Phenylephrine Hydrochloride), Nezger Tab(Ac... show more » |
| Category: | Antihistamines |
| CAS number: | 147-20-6 |
Pharmacology
| Indication: | For use in the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
|---|---|
| Pharmacology: |
Diphenylpyraline is an antihistamine that prevents, but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying ...
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| Mechanism of Action: | Antihistamines such as diphenylpyraline used in the treatment of allergy act by competing with histamine for H1-receptor sites on effector cells. This reduces the effects of histamine, leading to a temporary reduction of allergy symptoms. |
| Absorption: | Well absorbed after oral administration. |
| Protein binding: | > 99% in human serum albumin |
| Biotransformation: | Hepatic |
| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
