QuickView for Dyrk1b (gene)

Gene Symbol:

DYRK1B Homo sapiens

Full name:

dual specificity tyrosine phosphorylation regulated kinase 1B

Synonyms:

AOMS3, MIRK, dual specificity tyrosine-phosphorylation-regulated kinase 1B, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B, minibrain-related kinase, mirk protein kinase

Genomic Location:

Chr 19: 45007830-45016681

Description:

This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants.

This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACGTG_MYC_Q2 ,  FAC1_01 ,  GCCATNTTG_YY1_Q6 ,  OSF2_Q6 ,  P53_02 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  AAAGACA_MIR511 ,  RACCACAR_AML_Q6 ,  AP2REP_01 ,  CHOP_01 ,  YY1_02 ,  MEF2_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-9

Cytogenetic Map:

19q13.2

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