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QuickView for E-cadherin (gene)


Gene Symbol:
Cdh1 Rattus norvegicus Rattus norvegicus
Full name:
cadherin 1
Synonyms:
cadherin-1, E-cadherin, epithelial cadherin, uvomorulin
Genomic Location:
Chr 19: 36442693-36512091
Description:
cell-cell adhesion molecule; may play a role in axonal growth and synase formation
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_031334
Protein Names
Q9JIV9
Q9R0T4
O35794



GO Molecular Function

beta-catenin binding | cadherin binding | cation binding | enzyme binding | protein domain specific binding | cytoskeletal protein binding | gamma-catenin binding | identical protein binding | ion binding | ankyrin binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | GTPase activating protein binding | protein phosphatase binding | alpha-catenin binding | protein dimerization activity | calcium ion binding | phosphatase binding | metal ion binding

GO Biological Process

brain development | protein homooligomerization | cell morphogenesis | positive regulation of macromolecule biosynthetic process | regulation of cysteine-type endopeptidase activity | blastocyst formation | regulation of intracellular protein transport | regulation of neurogenesis | developmental process involved in reproduction | protein localization to cell periphery | regulation of cellular localization | regulation of cell development | regulation of localization | regulation of programmed cell death | cellular response to indole-3-methanol | negative regulation of cellular process | cell-cell adhesion mediated by cadherin | uterine epithelium development | response to metal ion | regulation of protein import | cell differentiation | maternal placenta development | nervous system development | response to drug | oviduct development | neurogenesis | positive regulation of cell adhesion | generation of neurons | sensory perception of mechanical stimulus | salivary gland morphogenesis | negative regulation of proteolysis | positive regulation of cellular biosynthetic process | cellular process | regulation of neuron migration | regulation of cell motility | localization | negative regulation of signaling | neuron development | regulation of branching involved in salivary gland morphogenesis | reproductive system development | synapse assembly | female pregnancy | multicellular organismal reproductive process | macromolecule localization | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | diencephalon development | response to inorganic substance | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | cell junction assembly | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | pituitary gland development | epithelium development | cellular response to organonitrogen compound | cellular component organization | cellular response to metal ion | head development | response to stimulus | cellular response to lithium ion | regulation of cellular protein localization | negative regulation of cell adhesion | gland morphogenesis | positive regulation of cellular protein localization | regulation of cell proliferation | multicellular organismal homeostasis | tube morphogenesis | positive regulation of cell-cell adhesion | epithelial cell development | reproduction | cellular response to inorganic substance | cellular localization | response to alcohol | cellular response to organic cyclic compound | regulation of protein transport | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | regulation of protein processing | intestinal epithelial cell development | regulation of peptide transport | regulation of cell adhesion | embryo development | regulation of morphogenesis of a branching structure | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | epithelial cell morphogenesis | regulation of intracellular transport | regulation of nucleic acid-templated transcription | water homeostasis | response to nitrogen compound | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | adherens junction organization | multicellular organism development | regulation of peptidase activity | oviduct epithelium development | response to amino acid | protein complex oligomerization | regulation of catalytic activity | regulation of protein localization to cell surface | trophectodermal cell differentiation | protein localization to plasma membrane | regulation of gene expression | salivary gland cavitation | protein localization to membrane | nervous system process | positive regulation of intracellular protein transport | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cysteine-type endopeptidase activity involved in apoptotic process | apical junction assembly | regulation of cellular component movement | response to lithium ion | synapse organization | bicellular tight junction assembly | positive regulation of protein localization to nucleus | regulation of cellular protein metabolic process | digestive tract development | response to toxic substance | cellular response to amino acid stimulus | endocrine system development | cell morphogenesis involved in differentiation | sensory organ development | cellular response to drug | negative regulation of cell-cell adhesion | chordate embryonic development | regulation of cellular metabolic process | sensory perception of sound | negative regulation of protein processing | regulation of protein metabolic process | inner ear development | homeostatic process | positive regulation of establishment of protein localization | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | positive regulation of transport | intestinal epithelial cell differentiation | decidualization | regulation of nucleocytoplasmic transport | neuron differentiation | multicellular organism reproduction | maternal process involved in female pregnancy | protein-containing complex assembly | negative regulation of epithelial cell proliferation | protein metabolic process | regulation of establishment of protein localization | response to organic substance | gland development | regulation of protein import into nucleus | digestive system development | response to antineoplastic agent | regulation of animal organ morphogenesis | anatomical structure development | cell projection organization | metabolic process | cell-cell junction assembly | regulation of RNA biosynthetic process | regulation of body fluid levels | cellular protein localization | ear development | chemical homeostasis | cell adhesion | neuron projection development | organic substance metabolic process | regulation of water loss via skin | negative regulation of gene expression | animal organ development | forebrain development | negative regulation of cellular protein metabolic process | regulation of Wnt signaling pathway | cell-cell adhesion | blastocyst development | positive regulation of intracellular transport | positive regulation of protein transport | anatomical structure formation involved in morphogenesis | uterus development | negative regulation of protein metabolic process | sensory perception | regulation of cell communication | negative regulation of signal transduction | regulation of transcription, DNA-templated | response to organic cyclic compound | response to indole-3-methanol | cell development | protein localization | regulation of epithelial cell proliferation | anatomical structure morphogenesis | regulation of endopeptidase activity | cellular macromolecule localization | positive regulation of protein import into nucleus | reproductive structure development | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of canonical Wnt signaling pathway | positive regulation of protein import | columnar/cuboidal epithelial cell development | tube development | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | regulation of cell-cell adhesion | multicellular organismal water homeostasis | positive regulation of nucleic acid-templated transcription | cochlea development | response to organonitrogen compound | epithelial cell differentiation | embryo implantation | tube formation | central nervous system development | cell-cell adhesion via plasma-membrane adhesion molecules | in utero embryonic development | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | placenta development | cellular response to organic substance | regulation of protein localization | exocrine system development | regulation of cell death | salivary gland development | positive regulation of nucleocytoplasmic transport | regulation of signaling | positive regulation of gene expression | homophilic cell adhesion via plasma membrane adhesion molecules | macromolecule metabolic process | multicellular organismal process | cell-cell junction organization

GO Cellular Component

integral component of membrane | cytoplasmic side of plasma membrane | intracellular membrane-bounded organelle | synapse | neuron projection | extrinsic component of membrane | catenin complex | adherens junction | cytoplasmic vesicle | cell | cytoplasmic side of membrane | plasma membrane protein complex | extrinsic component of plasma membrane | distal axon | intrinsic component of membrane | lamellipodium | compact myelin | cytoplasm | cortical cytoskeleton | intracellular organelle | actin cytoskeleton | membrane microdomain | main axon | apical part of cell | cell-cell adherens junction | presynapse | cell-cell junction | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | cell leading edge | lateral loop | membrane raft | vesicle | perinuclear region of cytoplasm | cytoplasmic region | node of Ranvier | cortical actin cytoskeleton | endosome | cell cortex | membrane-bounded organelle | apical junction complex | organelle | axon terminus | flotillin complex | cell periphery | axon | basolateral plasma membrane | trans-Golgi network | Schmidt-Lanterman incisure | neuron projection terminus | plasma membrane raft | intracellular vesicle | cell surface | cytoskeleton | intracellular | cell junction | myelin sheath | caveola | lateral plasma membrane | membrane