QuickView for E2F7;jsessionid=DF3FB09F3D48514796170E68146687DE (gene)
- Gene Symbol:
- E2F7
Homo sapiens - Full name:
- E2F transcription factor 7
- Synonyms:
- transcription factor E2F7, E2F-7
- Genomic Location:
- Chr 12: 75939157-75983491
- Description:
-
E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression (Di Stefano et al., 2003 [PubMed 14633988]).
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-10 , Predicted Gene Targets for miR-128 , Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-142-5p , Predicted Gene Targets for miR-148 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-26 , Predicted Gene Targets for miR-27 , Predicted Gene Targets for miR-30
- Cytogenetic Map:
-
12q21.2
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcription corepressor activity | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription coregulator activity | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | negative regulation of cell division | developmental process involved in reproduction | intracellular signal transduction | chorionic trophoblast cell differentiation | regulation of cell cycle G1/S phase transition | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | regulation of G1/S transition of mitotic cell cycle | regulation of DNA replication | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular process | mitotic DNA integrity checkpoint | negative regulation of G1/S transition of mitotic cell cycle | reproductive system development | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | hepaticobiliary system development | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | signal transduction involved in mitotic DNA damage checkpoint | negative regulation of cytokinesis | regulation of cell division | sprouting angiogenesis | response to stimulus | vasculature development | regulation of mitotic cell cycle phase transition | response to stress | trophoblast giant cell differentiation | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | regulation of cell cycle phase transition | reproduction | cardiovascular system development | cellular nitrogen compound metabolic process | cell cycle G1/S phase transition | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | embryo development | embryonic placenta development | blood vessel development | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | negative regulation of mitotic cell cycle phase transition | DNA damage response, signal transduction by p53 class mediator | mitotic DNA damage checkpoint | multicellular organism development | positive regulation of DNA replication | cellular response to DNA damage stimulus | positive regulation of cell cycle | signal transduction in response to DNA damage | regulation of gene expression | cellular response to stress | cell cycle | regulation of cell cycle arrest | positive regulation of cellular metabolic process | liver development | regulation of nitrogen compound metabolic process | regulation of DNA endoreduplication | transcription corepressor activity | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | biosynthetic process | cell differentiation involved in embryonic placenta development | aromatic compound biosynthetic process | angiogenesis | hepatocyte differentiation | signal transduction involved in cell cycle checkpoint | regulation of DNA-dependent DNA replication | mitotic cell cycle phase transition | mitotic G1 DNA damage checkpoint | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of cytokinesis | regulation of transcription involved in G1/S transition of mitotic cell cycle | G1/S transition of mitotic cell cycle | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | regulation of mitotic cell cycle | positive regulation of cell cycle arrest | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | gland development | G1 DNA damage checkpoint | anatomical structure development | mitotic cell cycle | positive regulation of DNA endoreduplication | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | embryonic organ development | negative regulation of mitotic cell cycle | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | positive regulation of DNA-dependent DNA replication | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | chorion development | signal transduction involved in mitotic cell cycle checkpoint | transcription, DNA-templated | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | negative regulation of cell cycle G1/S phase transition | signaling | regulation of transcription, DNA-templated | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | signal transduction involved in DNA damage checkpoint | reproductive structure development | positive regulation of DNA metabolic process | developmental process | positive regulation of cell cycle process | mitotic G1/S transition checkpoint | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | cell cycle phase transition | transcription coregulator activity | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | signal transduction involved in mitotic G1 DNA damage checkpoint | in utero embryonic development | positive regulation of metabolic process | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | placenta development | DNA damage checkpoint | cell cycle checkpoint | signal transduction by p53 class mediator | circulatory system development | negative regulation of transcription involved in G1/S transition of mitotic cell cycle | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
