QuickView for EIF2AK1;jsessionid=6D3E08C58BAFEDA659A1F338CEF9EC38 (gene)

Gene Symbol:

EIF2AK1 Homo sapiens

Full name:

eukaryotic translation initiation factor 2 alpha kinase 1

Synonyms:

HCR, HRI, eukaryotic translation initiation factor 2-alpha kinase 1, heme regulated initiation factor 2 alpha kinase, heme sensitive initiation factor 2a kinase, heme-controlled repressor, heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, heme-regulated inhibitor, heme-regulated repressor, hemin-sensitive initiation factor 2-alpha kinase

Genomic Location:

Chr 7: 6029988-6065302

Description:

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGCGGR_SP1_Q6 ,  SCGGAAGY_ELK1_02

Cytogenetic Map:

7p22.1

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