QuickView for ELMO1 (gene)

Gene Symbol:

ELMO1 Homo sapiens

Full name:

engulfment and cell motility 1

Synonyms:

CED-12, CED12, ELMO-1, engulfment and cell motility protein 1, ced-12 homolog 1

Genomic Location:

Chr 7: 36860486-37455036

Description:

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associate...

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This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  E12_Q6 ,  PR_Q2 ,  GATTGGY_NFY_Q6_01 ,  MYOD_Q6_01 ,  CACTGTG_MIR128A_MIR128B ,  RTAAACA_FREAC2_01 ,  FREAC7_01 ,  PR_02 ,  PU1_Q6 ,  MYOD_01 ,  TAL1ALPHAE47_01 ,  ETS_Q4 ,  TGGNNNNNNKCCAR_UNKNOWN ,  RSRFC4_01 ,  PR_01 ,  NFY_C ,  YATTNATC_UNKNOWN ,  AACTGGA_MIR145 ,  CTTTGA_LEF1_Q2 ,  ACTGTGA_MIR27A_MIR27B ,  TCF4_Q5 ,  GGGNRMNNYCAT_UNKNOWN ,  STAT_Q6 ,  TATAAA_TATA_01 ,  AR_Q6 ,  TAL1BETAE47_01 ,  PAX4_02 ,  GGATTA_PITX2_Q2 ,  NFY_Q6_01 ,  RFX1_02 ,  CAGGTG_E12_Q6 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  ETS2_B ,  LHX3_01 ,  NKX62_Q2 ,  GGCNRNWCTTYS_UNKNOWN ,  NFY_01 ,  YKACATTT_UNKNOWN ,  MGGAAGTG_GABP_B ,  GTTGNYNNRGNAAC_UNKNOWN ,  STAT3_01 ,  TGTYNNNNNRGCARM_UNKNOWN ,  AREB6_03 ,  TTGCCAA_MIR182 ,  FREAC2_01 ,  HAND1E47_01 ,  ELK1_01 ,  POU3F2_02 ,  TAATTA_CHX10_01 ,  GR_01 ,  MSX1_01 ,  WTTGKCTG_UNKNOWN ,  YTAATTAA_LHX3_01 ,  RGAGGAARY_PU1_Q6 ,  CTGCAGY_UNKNOWN ,  TTCYNRGAA_STAT5B_01 ,  TAL1BETAITF2_01 ,  TGACAGNY_MEIS1_01 ,  TBP_01 ,  NFKB_Q6_01 ,  P300_01 ,  BRN2_01 ,  AACTTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  TGACATY_UNKNOWN ,  ETS1_B ,  ELF1_Q6 ,  GTTRYCATRR_UNKNOWN ,  AAGCACA_MIR218 ,  LMO2COM_01 ,  STAT5A_02

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182

Cytogenetic Map:

7p14.2-p14.1

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