QuickView for EMT (gene)

Gene Symbol:

ITK Homo sapiens

Full name:

IL2 inducible T cell kinase

Synonyms:

EMT, LPFS1, LYK, PSCTK2, tyrosine-protein kinase ITK/TSK, IL-2-inducible T-cell kinase, T-cell-specific kinase, homolog of mouse T-cell itk/tsk, interleukin-2-inducible T-cell kinase, kinase EMT, tyrosine-protein kinase LYK

Genomic Location:

Chr 5: 156540485-156614687

Description:

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTTTGA_LEF1_Q2 ,  TGAYRTCA_ATF3_Q6 ,  AGCATTA_MIR155 ,  CEBPB_01 ,  ATF1_Q6 ,  BRN2_01 ,  TGACATY_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-155

Cytogenetic Map:

5q33.3

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