QuickView for EPHB6 (gene)
- Gene Symbol:
- EPHB6
Homo sapiens - Full name:
- EPH receptor B6
- Synonyms:
- HEP, ephrin type-B receptor 6, human kinase-defective Eph-family receptor protein, tyrosine-protein kinase-defective receptor EPH-6
- Genomic Location:
- Chr 7: 142262914-142278969
- Description:
-
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor prog...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
7q34
GO Molecular Function
transmembrane receptor protein tyrosine kinase activity | transmembrane signaling receptor activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | transmembrane-ephrin receptor activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | ephrin receptor activity | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of ERK1 and ERK2 cascade | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | negative regulation of cellular process | cell differentiation | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | cellular process | negative regulation of signaling | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | ephrin receptor signaling pathway | response to stimulus | positive regulation of protein metabolic process | transmembrane-ephrin receptor activity | protein modification process | macromolecule modification | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | phosphorus metabolic process | regulation of phosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | ephrin receptor activity | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | protein tyrosine kinase activity | protein metabolic process | positive regulation of protein modification process | regulation of intracellular signal transduction | cell surface receptor signaling pathway | metabolic process | negative regulation of programmed cell death | protein kinase activity | organic substance metabolic process | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | positive regulation of MAPK cascade | regulation of cell communication | negative regulation of signal transduction | signaling | positive regulation of phosphorylation | cellular protein metabolic process | kinase activity | developmental process | cellular protein modification process | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | neuron projection | cell | intrinsic component of membrane | cytoplasm | receptor complex | protein-containing complex | cell projection | plasma membrane | integral component of plasma membrane | extracellular region | cell periphery | cytosol | intracellular | membrane | intrinsic component of plasma membrane
