QuickView for EPX (gene)

Gene Symbol:

EPX Homo sapiens

Full name:

eosinophil peroxidase

Synonyms:

EPO, EPP, EPX-PEN, EPXD, eosinophil peroxidase

Genomic Location:

Chr 17: 53625088-53636783

Description:

This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of proto...

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This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA3_01 ,  GATA_Q6 ,  GATAAGR_GATA_C ,  TATAAA_TATA_01 ,  TGTYNNNNNRGCARM_UNKNOWN ,  GATA1_05

Cytogenetic Map:

17q22

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