QuickView for EXOC4;jsessionid=465FFD5B164A3A29E5CB79D5E802CE66 (gene)

Gene Symbol:

EXOC4 Homo sapiens

Full name:

exocyst complex component 4

Synonyms:

SEC8, SEC8L1, Sec8p, exocyst complex component 4, SEC8-like 1, exocyst complex component Sec8

Genomic Location:

Chr 7: 132588363-133401054

Description:

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes....

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The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TCCCRNNRTGC_UNKNOWN ,  TTGCCAA_MIR182 ,  TTGTTT_FOXO4_01 ,  YNGTTNNNATT_UNKNOWN

Cytogenetic Map:

7q33

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