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QuickView for EXOG;jsessionid=0E5DBFF4F6E4DD974C0414C201E206BF (gene)


Gene Symbol:
EXOG Homo sapiens Homo sapiens
Full name:
exo/endonuclease G
Synonyms:
ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b, ENGLA, ENGLB, nuclease EXOG, mitochondrial, endo G-like 1, endo/exonuclease (5'-3'), endonuclease G-like, endonuclease G-like 1, endonuclease G-like 2
Genomic Location:
Chr 3: 38512837-38541183
Description:
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on c...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3p22.2





GO Molecular Function

nuclease activity | cation binding | nucleic acid binding | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | endonuclease activity | exonuclease activity | metal ion binding | heterocyclic compound binding | 5'-3' exonuclease activity

GO Biological Process

nuclease activity | cellular process | organic substance catabolic process | DNA catabolic process, endonucleolytic | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | aromatic compound catabolic process | DNA metabolic process | cellular macromolecule catabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | endonuclease activity | DNA catabolic process | exonuclease activity | heterocycle metabolic process | 5'-3' exonuclease activity | cellular metabolic process | macromolecule metabolic process

GO Cellular Component

organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | cytoplasm | intracellular organelle | protein-containing complex | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane