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QuickView for EXOSC7;jsessionid=48F476EEDA5C0C6C45D14ECEB383885F (gene)


Gene Symbol:
EXOSC7 Homo sapiens Homo sapiens
Full name:
exosome component 7
Synonyms:
EAP1, RRP42, Rrp42p, hRrp42p, p8, exosome complex component RRP42, exosome complex exonuclease RRP42, ribosomal RNA-processing protein 42
Genomic Location:
Chr 3: 44992768-45027966
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3p21.31





GO Molecular Function

nuclease activity | 3'-5'-exoribonuclease activity | nucleic acid binding | exoribonuclease activity | hydrolase activity | ribonuclease activity | catalytic activity | hydrolase activity, acting on ester bonds | exoribonuclease activity, producing 5'-phosphomonoesters | AU-rich element binding | organic cyclic compound binding | protein binding | 3'-5' exonuclease activity | exonuclease activity | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | RNA surveillance | snRNA metabolic process | RNA processing | nuclease activity | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3'-5'-exoribonuclease activity | nuclear-transcribed mRNA catabolic process, exonucleolytic | cellular process | organic substance catabolic process | maturation of 5.8S rRNA | ribosome biogenesis | polyadenylation-dependent mRNA catabolic process | regulation of mRNA stability | regulation of cellular process | regulation of metabolic process | catabolic process | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | mRNA catabolic process | exoribonuclease activity | posttranscriptional regulation of gene expression | ncRNA 3'-end processing | ncRNA processing | cellular nitrogen compound metabolic process | nuclear RNA surveillance | nucleic acid phosphodiester bond hydrolysis | negative regulation of metabolic process | mRNA metabolic process | ribonuclease activity | nuclear-transcribed mRNA catabolic process | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | tRNA catabolic process | nuclear polyadenylation-dependent tRNA catabolic process | U4 snRNA 3'-end processing | regulation of gene expression | RNA catabolic process | nuclear polyadenylation-dependent ncRNA catabolic process | regulation of nitrogen compound metabolic process | regulation of RNA stability | nuclear mRNA surveillance | nuclear polyadenylation-dependent rRNA catabolic process | cleavage involved in rRNA processing | exoribonuclease activity, producing 5'-phosphomonoesters | U5 snRNA 3'-end processing | rRNA metabolic process | rRNA catabolic process | regulation of cellular metabolic process | snRNA processing | aromatic compound catabolic process | polyadenylation-dependent RNA catabolic process | regulation of RNA metabolic process | rRNA processing | tRNA metabolic process | snRNA 3'-end processing | rRNA 3'-end processing | cellular macromolecule catabolic process | metabolic process | RNA 3'-end processing | 3'-5' exonuclease activity | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | regulation of mRNA catabolic process | RNA phosphodiester bond hydrolysis | gene expression | RNA phosphodiester bond hydrolysis, exonucleolytic | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | U1 snRNA 3'-end processing | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' | exonuclease activity | ncRNA metabolic process | heterocycle metabolic process | ribonucleoprotein complex biogenesis | nuclear polyadenylation-dependent mRNA catabolic process | cellular metabolic process | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | exosome (RNase complex) | nuclear exosome (RNase complex) | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoplasmic exosome (RNase complex) | cytosol | intracellular