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QuickView for Esrrb (gene)


Gene Symbol:
ESRRB Homo sapiens Homo sapiens
Full name:
estrogen related receptor beta
Synonyms:
DFNB35, ERR2, ERRb, ESRL2, NR3B2, steroid hormone receptor ERR2, ERR beta-2, ERR-beta, ERRbeta-2, estrogen receptor-like 2, estrogen-related nuclear receptor beta, nuclear receptor ERRB2, nuclear receptor subfamily 3 group B member 2, orphan nuclear receptor
Genomic Location:
Chr 14: 75907479-76036961
Description:
This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 14
14q24.3





GO Molecular Function

sequence-specific DNA binding | RNA polymerase II complex binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | RNA polymerase binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | lipid binding | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | steroid hormone receptor activity | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | RNA polymerase core enzyme binding | ion binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | transition metal ion binding | steroid binding | transcription coregulator activity | metal ion binding | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of glycogen biosynthetic process | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | developmental process involved in reproduction | positive regulation of ATP metabolic process | regulation of carbohydrate metabolic process | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | positive regulation of phosphate metabolic process | tissue homeostasis | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | nuclear receptor activity | regulation of glycolytic process | reproductive system development | transcription factor activity, direct ligand regulated sequence-specific DNA binding | stem cell population maintenance | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | anatomical structure homeostasis | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | positive regulation of transcription involved in G1/S transition of mitotic cell cycle | regulation of cell division | response to stimulus | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding | cellular nitrogen compound biosynthetic process | multicellular organismal homeostasis | reproduction | cellular nitrogen compound metabolic process | regulation of stem cell population maintenance | cell cycle G1/S phase transition | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | embryo development | embryonic placenta development | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | cell dedifferentiation | multicellular organism development | regulation of phosphorylation | regulation of gene expression | response to lipid | cell cycle | stem cell division | positive regulation of cellular metabolic process | positive regulation of ATP biosynthetic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | positive regulation of glycolytic process | biosynthetic process | cell division | aromatic compound biosynthetic process | G2/M transition of mitotic cell cycle | mitotic cell cycle phase transition | sensory organ development | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of transcription involved in G1/S transition of mitotic cell cycle | inner ear development | cell cycle G2/M phase transition | homeostatic process | G1/S transition of mitotic cell cycle | embryo development ending in birth or egg hatching | transcription coactivator activity | regulation of RNA metabolic process | regulation of stem cell differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regulation of transcription involved in G2/M transition of mitotic cell cycle | response to organic substance | anatomical structure development | mitotic cell cycle | regulation of glucose metabolic process | metabolic process | positive regulation of glucose metabolic process | regulation of RNA biosynthetic process | embryonic organ development | ear development | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | maintenance of cell number | animal organ development | gene expression | retina homeostasis | photoreceptor cell maintenance | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | negative regulation of stem cell differentiation | regulation of ATP metabolic process | regulation of phosphate metabolic process | cellular response to steroid hormone stimulus | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | intracellular receptor signaling pathway | positive regulation of carbohydrate metabolic process | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | positive regulation of phosphorylation | cellular macromolecule biosynthetic process | positive regulation of stem cell population maintenance | reproductive structure development | regulation of developmental process | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | cell cycle phase transition | transcription coregulator activity | regulation of glycogen biosynthetic process | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of generation of precursor metabolites and energy | in utero embryonic development | positive regulation of metabolic process | cellular metabolic process | placenta development | regulation of stem cell division | cellular response to organic substance | response to steroid hormone | negative regulation of cell differentiation | signal transduction | positive regulation of transcription involved in G2/M transition of mitotic cell cycle | positive regulation of gene expression | regulation of glycogen metabolic process | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integrator complex | chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | condensed chromosome