Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for EthA (gene)


Gene Symbol:
SCN9A Homo sapiens Homo sapiens
Full name:
sodium voltage-gated channel alpha subunit 9
Synonyms:
ETHA, FEB3B, GEFSP7, HSAN2D, NE-NA, NENA, Nav1.7, PN1, SFNP, sodium channel protein type 9 subunit alpha, hNE-Na, neuroendocrine sodium channel, peripheral sodium channel 1, sodium channel protein type IX subunit alpha, sodium channel, voltage-gated, type IX, alpha polypeptide, sodium channel, voltage-gated, type IX, alpha subunit, voltage-gated sodium channel alpha subunit Nav1.7, voltage-gated sodium channel subunit alpha Nav1.7
Genomic Location:
Chr 2: 166759941-166876560
Description:
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2q24.3





GO Molecular Function

voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | voltage-gated sodium channel activity | transmembrane transporter activity | ion gated channel activity | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | metal ion transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | sodium ion binding | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | metal ion binding | ion channel activity | substrate-specific channel activity

GO Biological Process

behavioral response to pain | regulation of localization | establishment of localization | defense response | membrane depolarization during action potential | voltage-gated ion channel activity | cellular process | localization | passive transmembrane transporter activity | metal ion transport | voltage-gated sodium channel activity | transmembrane transporter activity | response to stimulus | ion gated channel activity | response to pain | response to stress | neuronal action potential | regulation of membrane potential | multicellular organism development | ion transmembrane transport | nervous system process | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | ion transmembrane transporter activity | sensory perception of pain | response to toxic substance | post-embryonic development | cell communication | inflammatory response | cation transmembrane transport | multicellular organismal response to stress | metal ion transmembrane transporter activity | anatomical structure development | behavior | membrane depolarization | sodium ion transmembrane transport | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | regulation of ion transmembrane transport | sodium channel activity | cation channel activity | sensory perception | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | developmental process | regulation of transport | transmission of nerve impulse | ion channel activity | ion transport | substrate-specific channel activity | multicellular organismal process

GO Cellular Component

integral component of membrane | voltage-gated sodium channel complex | neuron projection | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | cell projection | plasma membrane | integral component of plasma membrane | sodium channel complex | cell periphery | axon | transmembrane transporter complex | cation channel complex | ion channel complex | membrane | intrinsic component of plasma membrane