QuickView for Exo1 (gene)

Gene Symbol:

EXO1 Homo sapiens

Full name:

exonuclease 1

Synonyms:

HEX1, hExoI, exonuclease 1, rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1

Genomic Location:

Chr 1: 240078158-240119671

Description:

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  AACWWCAANK_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  ACTAYRNNNCCCR_UNKNOWN

Cytogenetic Map:

1q43

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