QuickView for FADS1 (gene)

Gene Symbol:

FADS1 Homo sapiens

Full name:

fatty acid desaturase 1

Synonyms:

D5D, FADS6, FADSD5, LLCDL1, TU12, fatty acid desaturase 1, delta(5) desaturase, delta-5 fatty acid desaturase, linoleoyl-CoA desaturase (delta-6-desaturase)-like 1

Genomic Location:

Chr 11: 61323679-61340886

Description:

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C...

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The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  CACTGTG_MIR128A_MIR128B ,  NFY_Q6_01 ,  NFY_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128

Cytogenetic Map:

11q12.2

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