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QuickView for FAS receptor (gene)


Gene Symbol:
Fas Rattus norvegicus Rattus norvegicus
Full name:
Fas cell surface death receptor
Synonyms:
Tnfrsf6, tumor necrosis factor receptor superfamily member 6, CD95 antigen, FASLG receptor, Fas (TNF receptor superfamily, member 6), Fas antigen (ATP1), Fas receptor, Tumor necrosis factor receptor superfamily, member 6, apo-1 antigen, apoptosis-mediating surface antigen FAS
Genomic Location:
Chr 1: 238259443-238274745
Description:
Tnfsf6/Fasl receptor
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_139194
Protein Names
Q63199
F1LWQ2



GO Molecular Function

kinase binding | transmembrane signaling receptor activity | enzyme binding | protein-containing complex binding | death receptor activity | signaling receptor activity | identical protein binding | protein binding | tumor necrosis factor-activated receptor activity | protease binding | calmodulin binding

GO Biological Process

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | leukocyte homeostasis | negative regulation of leukocyte activation | response to extracellular stimulus | brain development | cellular response to increased oxygen levels | protein homooligomerization | adaptive immune response | regulation of extrinsic apoptotic signaling pathway in absence of ligand | cellular response to decreased oxygen levels | regulation of cysteine-type endopeptidase activity | response to nutrient levels | negative regulation of immune system process | response to cytokine | response to interleukin-1 | cellular response to glucose stimulus | positive regulation of cellular component organization | regulation of B cell activation | response to lipopolysaccharide | developmental process involved in reproduction | motor neuron apoptotic process | positive regulation of apoptotic process | gonad development | regulation of programmed cell death | female gonad development | response to cycloheximide | necroptotic process | epithelial cell apoptotic process | regulation of immune system process | response to hormone | cellular response to hyperoxia | neuron death | negative regulation of cellular process | dendrite regeneration | response to metal ion | cellular response to tumor necrosis factor | cell differentiation | male gamete generation | nervous system development | cellular response to extracellular stimulus | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | response to water | response to drug | cellular chemical homeostasis | neurogenesis | glucose homeostasis | positive regulation of phosphate metabolic process | regulation of protein oligomerization | generation of neurons | response to antibiotic | negative T cell selection | regulation of neuron death | necroptotic signaling pathway | cellular process | lymphocyte differentiation | cellular homeostasis | extrinsic apoptotic signaling pathway | neuron development | reproductive system development | programmed necrotic cell death | female pregnancy | immune system development | multicellular organismal reproductive process | negative regulation of apoptotic process | response to hypoxia | cellular response to starvation | regulation of proteolysis | response to growth factor | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | response to inorganic substance | response to peptide hormone | regulation of cell differentiation | gamete generation | regulation of lymphocyte apoptotic process | regeneration | response to hydrogen peroxide | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | hepaticobiliary system development | cellular response to cobalt ion | positive regulation of cellular protein metabolic process | negative thymic T cell selection | cellular response to organonitrogen compound | cellular component organization | cellular response to metal ion | T cell activation | inflammatory cell apoptotic process | development of primary sexual characteristics | head development | response to stimulus | cellular response to lithium ion | cellular response to mechanical stimulus | positive regulation of protein metabolic process | positive regulation of peptidase activity | cellular response to hypoxia | response to stress | negative regulation of lymphocyte activation | regulation of cell proliferation | ovarian follicle atresia | ovulation cycle | response to peptide | positive regulation of cysteine-type endopeptidase activity | cellular response to hydrostatic pressure | circadian rhythm | response to glucose | response to starvation | programmed cell death | development of primary female sexual characteristics | reproduction | cellular response to inorganic substance | Fas signaling pathway | response to alcohol | rhythmic process | positive regulation of proteolysis | response to molecule of bacterial origin | cellular response to toxic substance | extrinsic apoptotic signaling pathway via death domain receptors | cellular response to organic cyclic compound | hemopoiesis | cellular component assembly | embryo development | regulation of lymphocyte differentiation | leukocyte differentiation | regulation of cellular response to stress | response to nitrogen compound | apoptotic process | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | response to external biotic stimulus | system development | cellular response to nutrient levels | response to oxygen levels | reproductive process | regulation of signal transduction | cellular response to antibiotic | multicellular organism development | cellular glucose homeostasis | regulation of peptidase activity | regulation of MAPK cascade | response to amino acid | protein complex oligomerization | leukocyte mediated immunity | spleen development | regulation of catalytic activity | cellular response to oxidative stress | regulation of phosphorylation | cellular response to amino acid starvation | telencephalon development | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | response to ketone | cellular response to stress | response to lipid | death receptor activity | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | liver development | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | neuron apoptotic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | cytokine-mediated signaling pathway | positive regulation of protein complex assembly | response to corticosteroid | response to lithium ion | response to oxidative stress | positive regulation of hydrolase activity | homeostasis of number of cells | T cell apoptotic process | cellular response to cytokine stimulus | neuron projection regeneration | regulation of cellular protein metabolic process | response to hyperoxia | hepatocyte apoptotic process | positive regulation of endopeptidase activity | positive regulation of neuron death | response to toxic substance | positive regulation of leukocyte apoptotic process | regulation of apoptotic signaling pathway | cellular response to amino acid stimulus | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | cellular response to drug | response to bacterium | response to estrogen | chordate embryonic development | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | liver regeneration | cellular response to estrogen stimulus | regulation of neuron apoptotic process | lymphocyte homeostasis | negative regulation of cell activation | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | response to monosaccharide | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | apoptotic signaling pathway | negative regulation of B cell activation | activation-induced cell death of T cells | lymphocyte activation | positive regulation of molecular function | neuron differentiation | multicellular organism reproduction | T cell differentiation | maternal process involved in female pregnancy | protein-containing complex assembly | regulation of protein homooligomerization | positive regulation of protein modification process | T cell selection | response to organic substance | gland development | T cell differentiation in thymus | regulation of hemopoiesis | response to mechanical stimulus | regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | immunoglobulin production | negative regulation of programmed cell death | cellular response to carbohydrate stimulus | cellular response to hydrogen peroxide | chemical homeostasis | positive regulation of cell death | immune response | cellular response to reactive oxygen species | neuron projection development | thymic T cell selection | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | tumor necrosis factor-activated receptor activity | animal organ development | response to reactive oxygen species | forebrain development | gene expression | regulation of cell activation | positive regulation of programmed cell death | tumor necrosis factor-mediated signaling pathway | regulation of phosphate metabolic process | renal system process | T cell homeostasis | cell activation | positive regulation of lymphocyte apoptotic process | response to fungicide | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | response to organic cyclic compound | cell development | positive regulation of protein homooligomerization | extrinsic apoptotic signaling pathway in absence of ligand | positive regulation of phosphorylation | response to hydrostatic pressure | regulation of endopeptidase activity | response to biotic stimulus | reproductive structure development | dendrite development | regulation of developmental process | B cell mediated immunity | developmental process | cellular response to interleukin-1 | spermatogenesis | cellular response to phenylalanine | positive regulation of protein oligomerization | necrotic cell death | response to organonitrogen compound | response to cobalt ion | response to amino acid starvation | central nervous system development | cellular response to water stimulus | positive regulation of metabolic process | immune system process | response to fluoride | hematopoietic or lymphoid organ development | female sex differentiation | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | sex differentiation | response to carbohydrate | response to steroid hormone | negative regulation of cell death | aging | carbohydrate homeostasis | sexual reproduction | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | animal organ regeneration | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | integral component of membrane | dendrite | intracellular membrane-bounded organelle | sarcolemma | apical plasma membrane | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | nuclear lumen | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | external side of plasma membrane | cytoplasm | death-inducing signaling complex | intracellular organelle | membrane microdomain | nuclear body | dendritic tree | apical part of cell | protein-containing complex | cell projection | secretory vesicle | endomembrane system | CD95 death-inducing signaling complex | nucleoplasm | plasma membrane | membrane raft | vesicle | perinuclear region of cytoplasm | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | apical dendrite | cell periphery | membrane-enclosed lumen | cytosol | intracellular vesicle | cell surface | intracellular | membrane