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QuickView for FAT4 (gene)


Gene Symbol:
FAT4 Homo sapiens Homo sapiens
Full name:
FAT atypical cadherin 4
Synonyms:
CDHF14, CDHR11, FAT-J, FATJ, HKLLS2, NBLA00548, VMLDS2, protocadherin Fat 4, FAT tumor suppressor homolog 4, cadherin family member 14, cadherin-related family member 11, fat-like cadherin protein FAT-J, putative protein product of Nbla00548
Genomic Location:
Chr 4: 126457017-126632373
Description:
The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants hav...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4q28.1





GO Molecular Function

cation binding | ion binding | protein binding | calcium ion binding | metal ion binding

GO Biological Process

brain development | Notch signaling pathway | regulation of epithelial cell differentiation involved in kidney development | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | intracellular signal transduction | morphogenesis of an epithelium | bone development | cell differentiation | nervous system development | neurogenesis | generation of neurons | membrane organization | cellular process | epithelial tube morphogenesis | heart morphogenesis | neuron development | renal tubule morphogenesis | endomembrane system organization | branching involved in ureteric bud morphogenesis | response to growth factor | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of nephron tubule epithelial cell differentiation | epithelium development | cellular component organization | urogenital system development | nephron tubule morphogenesis | head development | response to stimulus | cellular response to fibroblast growth factor stimulus | tube morphogenesis | regulation of epithelial cell differentiation | inner ear receptor cell differentiation | kidney development | system development | ureteric bud development | multicellular organism development | inner ear receptor cell development | inner ear receptor cell stereocilium organization | kidney morphogenesis | fibroblast growth factor receptor signaling pathway | regulation of metanephric nephron tubule epithelial cell differentiation | plasma membrane organization | mechanoreceptor differentiation | telencephalon development | kidney epithelium development | hippo signaling | animal organ morphogenesis | enzyme linked receptor protein signaling pathway | cell proliferation | mesonephric epithelium development | digestive tract development | mesonephros development | sensory organ development | cell communication | renal tubule development | inner ear development | heart development | renal system development | cerebral cortex development | ossification involved in bone maturation | nephron development | neuron differentiation | ureteric bud morphogenesis | response to organic substance | tissue morphogenesis | digestive system development | branching morphogenesis of an epithelial tube | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | condensed mesenchymal cell proliferation | developmental maturation | ear development | cell adhesion | neuron projection development | mesenchymal cell proliferation | nephron morphogenesis | animal organ development | forebrain development | pallium development | cell-cell adhesion | morphogenesis of a branching epithelium | bone maturation | signaling | cell development | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of developmental process | developmental process | tube development | response to fibroblast growth factor | central nervous system development | cell-cell adhesion via plasma-membrane adhesion molecules | transmembrane receptor protein tyrosine kinase signaling pathway | ossification | skeletal system development | cellular response to organic substance | circulatory system development | nephron tubule development | signal transduction | mesonephric tubule development | cellular response to growth factor stimulus | homophilic cell adhesion via plasma membrane adhesion molecules | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | apical part of cell | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | intracellular | membrane