QuickView for FBXL20;jsessionid=E67F4C55E6E512A8622682D946C6AAEB (gene)
- Gene Symbol:
- FBXL20
Homo sapiens - Full name:
- F-box and leucine rich repeat protein 20
- Synonyms:
- Fbl2, Fbl20, F-box/LRR-repeat protein 20, F-box protein FBL2
- Genomic Location:
- Chr 17: 34670366-34811402
- Description:
-
Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets thro...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Pan troglodytes , Bos taurus , Canis lupus familiaris , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
17q12
GO Molecular Function
catalytic activity | ubiquitin-like protein transferase activity | protein binding | ubiquitin-protein transferase activity | transferase activity
GO Biological Process
behavioral fear response | proteolysis | defense response | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | catabolic process | response to stimulus | response to stress | cellular protein catabolic process | proteasomal protein catabolic process | protein modification process | macromolecule modification | nitrogen compound metabolic process | protein catabolic process | protein modification by small protein conjugation | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | multicellular organismal response to stress | fear response | protein metabolic process | protein ubiquitination | cellular macromolecule catabolic process | metabolic process | ubiquitin-protein transferase activity | behavior | organic substance metabolic process | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | cellular protein metabolic process | behavioral defense response | cellular protein modification process | cellular metabolic process | modification-dependent protein catabolic process | post-translational protein modification | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
catalytic complex | cell | cytoplasm | ubiquitin ligase complex | protein-containing complex | transferase complex | cullin-RING ubiquitin ligase complex | SCF ubiquitin ligase complex | cytosol | intracellular
