QuickView for FCGR2B (gene)

Gene Symbol:

FCGR2B Homo sapiens

Full name:

Fc fragment of IgG receptor IIb

Synonyms:

CD32, CD32B, FCG2, FCGR2, IGFR2, low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc fragment of IgG, low affinity II, receptor for (CD32), Fc fragment of IgG, low affinity IIb, receptor (CD32), Fc fragment of IgG, low affinity IIb, receptor for (CD32), Fc gamma RIIb, Fc gamma receptor IIb, fc-gamma RII-b, fc-gamma-RIIb, fcRII-b, igG Fc receptor II-b

Genomic Location:

Chr 1: 159899564-159914575

Description:

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript...

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The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  IRF1_Q6 ,  GGGAGGRR_MAZ_Q6 ,  NERF_Q2 ,  IRF_Q6

Cytogenetic Map:

1q23.3

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