QuickView for FCGR3A (gene)
- Gene Symbol:
- FCGR3A
Homo sapiens - Full name:
- Fc fragment of IgG receptor IIIa
- Synonyms:
- CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20, low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc fragment of IgG low affinity IIIa receptor, Fc fragment of IgG, low affinity III, receptor for (CD16), Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc gamma receptor III-A, Fc gamma receptor IIIa, Fc-gamma RIII-alpha, Fc-gamma RIIIa, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), FcgammaRIIIA, fc-gamma RIII, igG Fc receptor III-2, immunoglobulin G Fc receptor III, neutrophil-specific antigen NA
- Genomic Location:
- Chr 1: 159778173-159786442
- Description:
-
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed o...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1q23.3
GO Molecular Function
protein-containing complex binding | immunoglobulin binding | IgG binding
GO Biological Process
positive regulation of immune response | immune response-regulating signaling pathway | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | immune response-activating cell surface receptor signaling pathway | cellular process | Fc-gamma receptor signaling pathway involved in phagocytosis | localization | regulation of immune response | regulation of cellular process | response to stimulus | positive regulation of immune system process | immune response-activating signal transduction | Fc-gamma receptor signaling pathway | vesicle-mediated transport | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | cell communication | activation of immune response | import into cell | cell surface receptor signaling pathway | endocytosis | immune response | signaling | Fc receptor signaling pathway | Fc receptor mediated stimulatory signaling pathway | immune system process | phagocytosis | signal transduction
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | cell surface | membrane
