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QuickView for FDPS (gene)


Gene Symbol:
FDPS Homo sapiens Homo sapiens
Full name:
farnesyl diphosphate synthase
Synonyms:
FPPS, FPS, POROK9, farnesyl pyrophosphate synthase, (2E,6E)-farnesyl diphosphate synthase, FPP synthase, FPP synthetase, farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase
Genomic Location:
Chr 1: 153545374-153557080
Description:
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q22





GO Molecular Function

cation binding | nucleic acid binding | transferase activity, transferring alkyl or aryl (other than methyl) groups | prenyltransferase activity | catalytic activity | dimethylallyltranstransferase activity | ion binding | geranyltranstransferase activity | organic cyclic compound binding | transferase activity | metal ion binding | heterocyclic compound binding | RNA binding

GO Biological Process

isoprenoid biosynthetic process | phospholipid metabolic process | sterol metabolic process | cellular process | terpenoid biosynthetic process | interspecies interaction between organisms | regulation of metabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | cellular lipid metabolic process | alcohol metabolic process | regulation of steroid biosynthetic process | cellular biosynthetic process | regulation of steroid metabolic process | organic hydroxy compound metabolic process | phosphorus metabolic process | lipid metabolic process | regulation of cholesterol biosynthetic process | organophosphate metabolic process | sterol biosynthetic process | phospholipid biosynthetic process | small molecule metabolic process | farnesyl diphosphate biosynthetic process | regulation of cholesterol metabolic process | biosynthetic process | cholesterol biosynthetic process | lipid biosynthetic process | phosphate-containing compound metabolic process | viral process | regulation of lipid biosynthetic process | metabolic process | cholesterol metabolic process | organic substance metabolic process | geranyl diphosphate biosynthetic process | steroid metabolic process | farnesyl diphosphate metabolic process | isoprenoid metabolic process | regulation of lipid metabolic process | cellular metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular