QuickView for FDPs (gene)
- Gene Symbol:
- FDPS
Homo sapiens - Full name:
- farnesyl diphosphate synthase
- Synonyms:
- FPPS, FPS, POROK9, farnesyl pyrophosphate synthase, (2E,6E)-farnesyl diphosphate synthase, FPP synthase, FPP synthetase, farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase
- Genomic Location:
- Chr 1: 153545374-153557080
- Description:
-
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and ...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1q22
GO Molecular Function
cation binding | nucleic acid binding | transferase activity, transferring alkyl or aryl (other than methyl) groups | prenyltransferase activity | catalytic activity | dimethylallyltranstransferase activity | ion binding | geranyltranstransferase activity | organic cyclic compound binding | transferase activity | metal ion binding | heterocyclic compound binding | RNA binding
GO Biological Process
isoprenoid biosynthetic process | phospholipid metabolic process | sterol metabolic process | cellular process | terpenoid biosynthetic process | interspecies interaction between organisms | regulation of metabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | cellular lipid metabolic process | alcohol metabolic process | regulation of steroid biosynthetic process | cellular biosynthetic process | regulation of steroid metabolic process | organic hydroxy compound metabolic process | phosphorus metabolic process | lipid metabolic process | regulation of cholesterol biosynthetic process | organophosphate metabolic process | sterol biosynthetic process | phospholipid biosynthetic process | small molecule metabolic process | farnesyl diphosphate biosynthetic process | regulation of cholesterol metabolic process | biosynthetic process | cholesterol biosynthetic process | lipid biosynthetic process | phosphate-containing compound metabolic process | viral process | regulation of lipid biosynthetic process | metabolic process | cholesterol metabolic process | organic substance metabolic process | geranyl diphosphate biosynthetic process | steroid metabolic process | farnesyl diphosphate metabolic process | isoprenoid metabolic process | regulation of lipid metabolic process | cellular metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
