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QuickView for FFAR1 (gene)


Gene Symbol:
FFAR1 Homo sapiens Homo sapiens
Full name:
free fatty acid receptor 1
Synonyms:
FFA1R, GPCR40, GPR40, free fatty acid receptor 1, G-protein coupled receptor 40
Genomic Location:
Chr 19: 40534295-40535197
Description:
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.12


Transcripts Names
NM_005303
Protein Names
Q4VBL4
Q0VAS2
O14842



GO Molecular Function

guanyl-nucleotide exchange factor activity | GTPase binding | transmembrane signaling receptor activity | enzyme binding | lipid binding | G-protein coupled receptor activity | molecular function regulator | bioactive lipid receptor activity | signaling receptor activity | protein binding

GO Biological Process

guanyl-nucleotide exchange factor activity | regulation of localization | hormone secretion | establishment of localization | glucose homeostasis | regulation of peptide hormone secretion | positive regulation of protein secretion | cellular process | secretion | peptide hormone secretion | localization | protein transport | macromolecule localization | regulation of cellular process | G-protein coupled receptor activity | regulation of peptide secretion | response to stimulus | regulation of insulin secretion | secretion by cell | positive regulation of hormone secretion | regulation of protein transport | G-protein coupled receptor signaling pathway | regulation of peptide transport | cell-cell signaling | insulin secretion | molecular function regulator | positive regulation of peptide secretion | response to fatty acid | regulation of hormone levels | regulation of hormone secretion | bioactive lipid receptor activity | positive regulation of secretion | organic substance transport | response to lipid | peptide transport | peptide secretion | cell communication | homeostatic process | positive regulation of establishment of protein localization | positive regulation of transport | positive regulation of peptide hormone secretion | regulation of establishment of protein localization | response to organic substance | positive regulation of insulin secretion | amide transport | chemical homeostasis | regulation of secretion | hormone transport | positive regulation of ion transport | regulation of protein secretion | establishment of protein localization | positive regulation of protein transport | regulation of cell communication | signaling | protein localization | regulation of ion transport | regulation of calcium ion transport | regulation of transport | signal release | regulation of protein localization | protein secretion | carbohydrate homeostasis | positive regulation of calcium ion transport | positive regulation of signaling | signal transduction | regulation of signaling

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane