QuickView for FGF10;jsessionid=1CC06D7A04845C52183B5DE9FB1D9685 (gene)
- Gene Symbol:
- FGF10
Homo sapiens - Full name:
- fibroblast growth factor 10
- Synonyms:
- fibroblast growth factor 10, FGF-10, keratinocyte growth factor 2, produced by fibroblasts of urinary bladder lamina propria
- Genomic Location:
- Chr 5: 44340854-44424541
- Description:
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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitoge...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
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5p12
GO Molecular Function
guanyl-nucleotide exchange factor activity | GTPase binding | enzyme binding | signaling receptor binding | carbohydrate derivative binding | Ras GTPase binding | molecular function regulator | catalytic activity | anion binding | phosphatidylinositol 3-kinase activity | fibroblast growth factor receptor binding | ion binding | heparin binding | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | protein tyrosine kinase activity | protein binding | receptor regulator activity | type 2 fibroblast growth factor receptor binding | 1-phosphatidylinositol-3-kinase activity | growth factor activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | Ras guanyl-nucleotide exchange factor activity | receptor ligand activity | protein kinase activity | chemoattractant activity | glycosaminoglycan binding | transferase activity | small GTPase binding | growth factor receptor binding | kinase activity
GO Biological Process
regulation of activin receptor signaling pathway | positive regulation of cyclin-dependent protein serine/threonine kinase activity | semicircular canal development | regulation of ERK1 and ERK2 cascade | brain development | limb development | molting cycle | branch elongation involved in salivary gland morphogenesis | inner ear morphogenesis | regulation of extrinsic apoptotic signaling pathway in absence of ligand | regulation of cell cycle process | positive regulation of ATPase activity | positive regulation of macromolecule biosynthetic process | prostatic bud formation | positive regulation of locomotion | actin filament-based process | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | guanyl-nucleotide exchange factor activity | positive regulation of Ras protein signal transduction | microtubule cytoskeleton organization involved in mitosis | epidermis morphogenesis | embryonic genitalia morphogenesis | cell motility | lung growth | response to lipopolysaccharide | developmental process involved in reproduction | intracellular signal transduction | mesenchymal-epithelial cell signaling | regulation of localization | regulation of cell cycle G1/S phase transition | mammary gland duct morphogenesis | otic vesicle development | morphogenesis of an epithelium | induction of positive chemotaxis | somatic stem cell population maintenance | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | peptidyl-amino acid modification | eye development | phosphatidylinositol metabolic process | actin cytoskeleton organization | smooth muscle cell differentiation | branching involved in salivary gland morphogenesis | establishment of localization | regulation of immune system process | response to hormone | mammary gland bud morphogenesis | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | positive regulation of lymphocyte activation | microtubule cytoskeleton organization | establishment of mitotic spindle orientation | otic vesicle formation | cell differentiation | positive regulation of epithelial cell proliferation | positive regulation of fibroblast proliferation | respiratory tube development | nervous system development | organ growth | epithelial cell migration | regulation of G1/S transition of mitotic cell cycle | neurogenesis | positive regulation of phosphate metabolic process | positive regulation of hair follicle cell proliferation | regulation of DNA replication | peptidyl-tyrosine phosphorylation | positive regulation of cellular component movement | phosphatidylinositol-3-phosphate biosynthetic process | mesenchyme development | positive regulation of white fat cell proliferation | salivary gland morphogenesis | phospholipid metabolic process | regulation of DNA repair | microtubule-based process | positive regulation of vascular endothelial growth factor receptor signaling pathway | blood vessel morphogenesis | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | secretion | establishment of organelle localization | positive regulation of keratinocyte migration | regulation of cell motility | localization | epithelial tube morphogenesis | limb morphogenesis | odontogenesis | tissue remodeling | negative regulation of signaling | developmental growth | regulation of branching involved in salivary gland morphogenesis | determination of left/right symmetry | reproductive system development | response to estradiol | regulation of vascular endothelial growth factor receptor signaling pathway | epithelium migration | mammary gland bud formation | immune system development | regulation of digestive system process | stem cell population maintenance | positive regulation of protein kinase activity | macromolecule localization | regulation of chemotaxis | negative regulation of apoptotic process | digestive tract morphogenesis | regulation of cell cycle | establishment of mitotic spindle localization | response to growth factor | positive regulation of catalytic activity | lung epithelium development | positive regulation of nitrogen compound metabolic process | diencephalon development | negative regulation of cell cycle arrest | regulation of canonical Wnt signaling pathway | regulation of smoothened signaling pathway | establishment of localization in cell | mammary gland specification | tissue development | regulation of cell differentiation | muscle structure development | muscle cell differentiation | negative regulation of apoptotic signaling pathway | regeneration | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | gliogenesis | pituitary gland development | organelle localization | positive regulation of cyclin-dependent protein kinase activity | positive regulation of cellular protein metabolic process | epithelium development | male genitalia morphogenesis | establishment of cell polarity | cellular component organization | positive regulation of response to DNA damage stimulus | cellular lipid metabolic process | prostate gland epithelium morphogenesis | epithelial tube branching involved in lung morphogenesis | MAPK cascade | lung proximal/distal axis specification | urogenital system development | positive regulation of epithelial cell migration | mammary gland morphogenesis | regulation of keratinocyte proliferation | head development | thyroid gland development | response to stimulus | thymus development | lacrimal gland development | vasculature development | respiratory system development | regulation of mitotic cell cycle phase transition | cellular response to fibroblast growth factor stimulus | regulation of peptidyl-tyrosine phosphorylation | blood vessel remodeling | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | gland morphogenesis | response to stress | regulation of ATPase activity | positive regulation of lymphocyte proliferation | regulation of cell proliferation | establishment of spindle localization | tube morphogenesis | regulation of cell cycle phase transition | positive regulation of cell activation | epithelial tube formation | reproduction | cellular localization | secretion by cell | cardiovascular system development | embryonic digestive tract morphogenesis | response to molecule of bacterial origin | axis elongation | metanephros morphogenesis | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | cellular biosynthetic process | kidney development | embryo development | regulation of morphogenesis of a branching structure | macromolecule modification | cell-cell signaling | activation of protein kinase activity | mammary gland formation | molecular function regulator | positive chemotaxis | blood vessel development | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | locomotion | lung alveolus development | positive regulation of mononuclear cell proliferation | response to external biotic stimulus | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | tear secretion | reproductive process | regulation of signal transduction | keratinocyte proliferation | semicircular canal morphogenesis | multicellular organism development | cell migration | positive regulation of DNA replication | regulation of MAPK cascade | phosphorus metabolic process | female genitalia morphogenesis | type II pneumocyte differentiation | mammary gland development | spindle localization | spleen development | positive regulation of keratinocyte proliferation | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | semicircular canal formation | regulation of phosphorylation | kidney morphogenesis | fibroblast growth factor receptor signaling pathway | hair follicle morphogenesis | embryonic digestive tract development | wound healing | positive regulation of cell cycle | determination of bilateral symmetry | positive regulation of mitotic cell cycle | regulation of small GTPase mediated signal transduction | regulation of gene expression | positive regulation of chemotaxis | lateral sprouting from an epithelium | regulation of extrinsic apoptotic signaling pathway | pancreas development | response to lipid | cell cycle | bronchiole morphogenesis | organophosphate metabolic process | Harderian gland development | regulation of cell cycle arrest | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | animal organ morphogenesis | phospholipid biosynthetic process | urothelial cell proliferation | specification of animal organ identity | positive regulation of Notch signaling pathway | limb bud formation | lung secretory cell differentiation | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of Notch signaling pathway | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | phosphatidylinositol 3-kinase activity | morphogenesis of an epithelial fold | fat cell differentiation | radial glial cell differentiation | positive regulation of hydrolase activity | positive regulation of urothelial cell proliferation | negative regulation of extrinsic apoptotic signaling pathway | establishment of spindle orientation | embryonic camera-type eye development | positive regulation of cell migration | cell proliferation | biosynthetic process | regulation of cellular protein metabolic process | glial cell differentiation | angiogenesis | phosphorylation | mesenchymal cell differentiation involved in lung development | digestive tract development | lipid biosynthetic process | semicircular canal fusion | epidermis development | regulation of apoptotic signaling pathway | skin development | protein localization to cell surface | endocrine system development | protein phosphorylation | bud elongation involved in lung branching | mesonephros development | establishment or maintenance of cell polarity | phosphate-containing compound metabolic process | sensory organ development | lipid phosphorylation | proximal/distal pattern formation | response to bacterium | animal organ formation | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | female genitalia development | metanephros development | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | odontogenesis of dentin-containing tooth | regulation of protein metabolic process | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling | positive regulation of signal transduction | inner ear development | lipid modification | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | glycerolipid metabolic process | regulation of RNA metabolic process | renal system development | genitalia development | regulation of cellular response to growth factor stimulus | embryonic morphogenesis | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | bud outgrowth involved in lung branching | regulation of mitotic cell cycle | regulation of white fat cell proliferation | protein tyrosine kinase activity | positive regulation of molecular function | lung epithelial cell differentiation | activation of MAPK activity | embryonic organ morphogenesis | regulation of signaling receptor activity | receptor regulator activity | protein metabolic process | regulation of fibroblast proliferation | regionalization | axis specification | positive regulation of protein modification process | hair cycle | response to organic substance | gland development | tissue morphogenesis | digestive system development | glycerophospholipid biosynthetic process | 1-phosphatidylinositol-3-kinase activity | branching morphogenesis of an epithelial tube | epithelial cell proliferation | regulation of kinase activity | male sex differentiation | response to wounding | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | regulation of saliva secretion | anatomical structure development | developmental growth involved in morphogenesis | branch elongation of an epithelium | mitotic cell cycle | cell surface receptor signaling pathway | positive regulation of small GTPase mediated signal transduction | growth factor activity | submandibular salivary gland formation | metabolic process | cell fate commitment | mesenchymal cell differentiation | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | regulation of body fluid levels | negative regulation of programmed cell death | embryonic organ development | cellular protein localization | ear development | actin cytoskeleton reorganization | bronchiole development | hair cycle process | Ras guanyl-nucleotide exchange factor activity | regulation of secretion | body fluid secretion | morphogenesis of embryonic epithelium | receptor ligand activity | regulation of response to DNA damage stimulus | male genitalia development | protein kinase activity | organic substance metabolic process | mesenchymal-epithelial cell signaling involved in lung development | maintenance of cell number | chemoattractant activity | animal organ development | positive regulation of epithelial cell proliferation involved in wound healing | forebrain development | proximal/distal axis specification | regulation of cell activation | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | skin epidermis development | regulation of Wnt signaling pathway | genitalia morphogenesis | regulation of phosphate metabolic process | cytoskeleton organization | mammary gland epithelium development | muscle cell fate commitment | phosphatidylinositol biosynthetic process | prostate gland morphogenesis | regulation of hair follicle cell proliferation | positive regulation of MAPK cascade | lung development | morphogenesis of a branching epithelium | camera-type eye development | positive regulation of canonical Wnt signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | regulation of epithelial cell migration | regulation of animal organ formation | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | protein localization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | regulation of Ras protein signal transduction | phosphatidylinositol phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | cellular macromolecule localization | positive regulation of MAP kinase activity | response to biotic stimulus | reproductive structure development | regulation of developmental process | glycerophospholipid metabolic process | positive regulation of DNA metabolic process | epithelial cell proliferation involved in salivary gland morphogenesis | kinase activity | developmental process | organelle organization | lung cell differentiation | cellular protein modification process | white fat cell differentiation | tube development | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | response to fibroblast growth factor | positive regulation of nucleic acid-templated transcription | lung morphogenesis | tube closure | epithelial cell differentiation | ERK1 and ERK2 cascade | positive regulation of transcription by RNA polymerase II | tube formation | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | organ induction | immune system process | positive regulation of Wnt signaling pathway | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of cell cycle process | female sex differentiation | ameboidal-type cell migration | cellular response to organic substance | exocrine system development | lung saccule development | regulation of cell death | sex differentiation | positive regulation of cell motility | salivary gland development | negative regulation of cell death | developmental induction | circulatory system development | chemotaxis | ear morphogenesis | tissue regeneration | secretion by lung epithelial cell involved in lung growth | fibroblast growth factor receptor signaling pathway involved in mammary gland specification | negative regulation of cell differentiation | otic vesicle morphogenesis | response to other organism | positive regulation of signaling | hair follicle development | signal transduction | regulation of signaling | positive regulation of gene expression | positive regulation of fat cell proliferation | embryonic pattern specification | positive regulation of DNA repair | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | positive regulation of positive chemotaxis | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | extracellular matrix | cell | intracellular organelle | plasma membrane | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cell periphery | cell surface | intracellular | membrane
