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QuickView for FGF21 (gene)


Gene Symbol:
FGF21 Homo sapiens Homo sapiens
Full name:
fibroblast growth factor 21
Synonyms:
fibroblast growth factor 21
Genomic Location:
Chr 19: 53951156-53953394
Description:
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in ad...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.33


Transcripts Names
NM_019113
Protein Names
Q8N683
Q9NSA1



GO Molecular Function

signaling receptor binding | molecular function regulator | fibroblast growth factor receptor binding | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | growth factor receptor binding

GO Biological Process

response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | positive regulation of macromolecule biosynthetic process | response to nutrient levels | response to endoplasmic reticulum stress | cellular response to glucose stimulus | regulation of localization | regulation of programmed cell death | positive regulation of lipid catabolic process | epithelial cell apoptotic process | response to hormone | negative regulation of neuron death | negative regulation of cellular process | response to drug | cellular chemical homeostasis | glucose homeostasis | positive regulation of phosphate metabolic process | regulation of neuron death | cellular process | regulation of glucose import | cellular homeostasis | endoplasmic reticulum unfolded protein response | negative regulation of apoptotic process | response to growth factor | positive regulation of nitrogen compound metabolic process | response to peptide hormone | cellular response to low-density lipoprotein particle stimulus | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular response to unfolded protein | cellular response to organonitrogen compound | response to topologically incorrect protein | cellular response to topologically incorrect protein | response to stimulus | negative regulation of epithelial cell apoptotic process | positive regulation of cold-induced thermogenesis | cellular response to fibroblast growth factor stimulus | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | response to peptide | positive regulation of glucose import | response to glucose | programmed cell death | regulation of triglyceride metabolic process | cell-cell signaling | molecular function regulator | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | regulation of signal transduction | response to activity | cellular glucose homeostasis | cellular response to peptide hormone stimulus | regulation of MAPK cascade | response to amino acid | regulation of phosphorylation | fibroblast growth factor receptor signaling pathway | cellular response to stress | cellular response to peptide | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | endothelial cell apoptotic process | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | response to methionine | regulation of endothelial cell apoptotic process | positive regulation of glucose transmembrane transport | regulation of cellular protein metabolic process | positive regulation of low-density lipoprotein particle receptor biosynthetic process | regulation of epithelial cell apoptotic process | cellular response to drug | cell communication | regulation of cellular metabolic process | regulation of lipid catabolic process | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of cell proliferation | response to monosaccharide | regulation of protein phosphorylation | positive regulation of transport | cellular response to lipoprotein particle stimulus | regulation of signaling receptor activity | receptor regulator activity | positive regulation of triglyceride metabolic process | response to glucagon | positive regulation of protein modification process | response to organic substance | regulation of intracellular signal transduction | cell surface receptor signaling pathway | growth factor activity | regulation of receptor biosynthetic process | negative regulation of programmed cell death | cellular response to carbohydrate stimulus | chemical homeostasis | receptor ligand activity | cell death | regulation of glucose transmembrane transport | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | positive regulation of MAPK cascade | regulation of cell communication | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway | signaling | positive regulation of phosphorylation | response to unfolded protein | positive regulation of triglyceride catabolic process | regulation of transport | response to fibroblast growth factor | response to organonitrogen compound | regulation of low-density lipoprotein particle clearance | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | positive regulation of receptor biosynthetic process | cellular response to organic substance | regulation of cell death | response to carbohydrate | negative regulation of cell death | carbohydrate homeostasis | cellular response to glucagon stimulus | positive regulation of signaling | regulation of low-density lipoprotein particle receptor biosynthetic process | signal transduction | regulation of signaling | negative regulation of endothelial cell apoptotic process | cellular response to growth factor stimulus | regulation of phosphorus metabolic process

GO Cellular Component

cell | extracellular region | extracellular space