QuickView for FGF4 (gene)
- Gene Symbol:
- FGF4
Homo sapiens - Full name:
- fibroblast growth factor 4
- Synonyms:
- FGF-4, HBGF-4, HST, HST-1, HSTF-1, HSTF1, K-FGF, KFGF, fibroblast growth factor 4, fibroblast growth factor 4 splice isoform, heparin secretory transforming protein 1, heparin-binding growth factor 4, human stomach cancer, transforming factor from FGF-related oncogene, kaposi sarcoma oncogene, oncogene HST, transforming protein KS3
- Genomic Location:
- Chr 11: 69296978-69299352
- Description:
-
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by it...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Danio rerio , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
11q13.3
GO Molecular Function
guanyl-nucleotide exchange factor activity | GTPase binding | enzyme binding | signaling receptor binding | carbohydrate derivative binding | Ras GTPase binding | molecular function regulator | catalytic activity | anion binding | phosphatidylinositol 3-kinase activity | fibroblast growth factor receptor binding | ion binding | heparin binding | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | protein tyrosine kinase activity | protein binding | receptor regulator activity | 1-phosphatidylinositol-3-kinase activity | growth factor activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | Ras guanyl-nucleotide exchange factor activity | receptor ligand activity | protein kinase activity | glycosaminoglycan binding | transferase activity | small GTPase binding | growth factor receptor binding | kinase activity
GO Biological Process
regulation of ERK1 and ERK2 cascade | limb development | positive regulation of macromolecule biosynthetic process | guanyl-nucleotide exchange factor activity | response to cytokine | cranial skeletal system development | intracellular signal transduction | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | phosphatidylinositol metabolic process | negative regulation of cellular process | embryonic appendage morphogenesis | bone development | cell differentiation | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | phosphatidylinositol-3-phosphate biosynthetic process | phospholipid metabolic process | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | limb morphogenesis | odontogenesis | cranial suture morphogenesis | stem cell population maintenance | regulation of chemotaxis | negative regulation of apoptotic process | response to growth factor | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | tissue development | hindlimb morphogenesis | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular lipid metabolic process | MAPK cascade | regulation of cell division | response to stimulus | cartilage condensation | embryonic limb morphogenesis | cellular response to fibroblast growth factor stimulus | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | craniofacial suture morphogenesis | regulation of cell proliferation | programmed cell death | regulation of endothelial cell chemotaxis to fibroblast growth factor | positive regulation of RNA biosynthetic process | protein modification process | cartilage development | cellular biosynthetic process | embryo development | macromolecule modification | cell-cell signaling | molecular function regulator | regulation of nucleic acid-templated transcription | apoptotic process | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | positive regulation of protein kinase B signaling | lipid metabolic process | regulation of phosphorylation | fibroblast growth factor receptor signaling pathway | regulation of gene expression | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | phospholipid biosynthetic process | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | phosphatidylinositol 3-kinase activity | regulation of endothelial cell migration | cellular response to cytokine stimulus | cell proliferation | biosynthetic process | regulation of cellular protein metabolic process | phosphorylation | lipid biosynthetic process | protein phosphorylation | phosphate-containing compound metabolic process | lipid phosphorylation | chondroblast differentiation | cell communication | regulation of cellular metabolic process | skeletal system morphogenesis | odontogenesis of dentin-containing tooth | regulation of protein metabolic process | positive regulation of signal transduction | apoptotic process involved in development | lipid modification | positive regulation of cell proliferation | regulation of protein phosphorylation | bone morphogenesis | regulation of locomotion | glycerolipid metabolic process | regulation of RNA metabolic process | regulation of cellular response to growth factor stimulus | embryonic hindlimb morphogenesis | embryonic morphogenesis | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | protein tyrosine kinase activity | regulation of signaling receptor activity | receptor regulator activity | protein metabolic process | positive regulation of protein modification process | response to organic substance | glycerophospholipid biosynthetic process | 1-phosphatidylinositol-3-kinase activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | Ras guanyl-nucleotide exchange factor activity | receptor ligand activity | protein kinase activity | mesenchymal cell proliferation | organic substance metabolic process | connective tissue development | maintenance of cell number | cell death | animal organ development | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | phosphatidylinositol biosynthetic process | positive regulation of MAPK cascade | regulation of epithelial cell migration | regulation of cell communication | cellular response to leukemia inhibitory factor | signaling | regulation of transcription, DNA-templated | positive regulation of phosphorylation | cellular protein metabolic process | phosphatidylinositol phosphorylation | anatomical structure morphogenesis | glycerophospholipid metabolic process | kinase activity | developmental process | cell aggregation | cellular protein modification process | positive regulation of transcription, DNA-templated | response to fibroblast growth factor | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | apoptotic process involved in morphogenesis | skeletal system development | cellular metabolic process | cellular response to organic substance | regulation of cell death | negative regulation of cell death | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
