QuickView for FKBP1B;jsessionid=92271347B9F0B06840E10B1EA524794E (gene)

Gene Symbol:

FKBP1B Homo sapiens

Full name:

FK506 binding protein 1B

Synonyms:

FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase, peptidyl-prolyl cis-trans isomerase FKBP1B, 12.6 kDa FK506-binding protein, 12.6 kDa FKBP, FK506 binding protein 1B, 12.6 kDa, FK506-binding protein 12.6, FKBP-12.6, FKBP-1B, PPIase FKBP1B, calstabin 2, h-FKBP-12, immunophilin FKBP12.6, rotamase

Genomic Location:

Chr 2: 24126132-24140055

Description:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1...

View Full Description

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

2p23.3

search → result