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QuickView for FLVCR1 (gene)


Gene Symbol:
FLVCR1 Homo sapiens Homo sapiens
Full name:
feline leukemia virus subgroup C cellular receptor 1
Synonyms:
AXPC1, FLVCR, MFSD7B, PCA, PCARP, feline leukemia virus subgroup C receptor-related protein 1
Genomic Location:
Chr 1: 211098220-211135379
Description:
This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder ...
Orthologs:
Mus musculus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio Rattus norvegicus
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1q32.3





GO Molecular Function

cofactor binding | transmembrane transporter activity | transporter activity | organic cyclic compound binding | tetrapyrrole binding | protein binding | heme transporter activity | heme binding | heterocyclic compound binding

GO Biological Process

limb development | erythrocyte homeostasis | establishment of localization | myeloid cell differentiation | embryonic appendage morphogenesis | cell differentiation | multicellular organism growth | cellular chemical homeostasis | erythrocyte maturation | cellular process | localization | cellular homeostasis | limb morphogenesis | cell maturation | developmental growth | immune system development | myeloid cell development | head morphogenesis | transmembrane transporter activity | head development | vasculature development | embryonic limb morphogenesis | heme export | embryonic skeletal system development | cardiovascular system development | hemopoiesis | embryo development | metal ion homeostasis | blood vessel development | myeloid cell homeostasis | system development | multicellular organism development | spleen development | organic substance transport | cellular ion homeostasis | animal organ morphogenesis | mitochondrial transport | homeostasis of number of cells | cation homeostasis | erythrocyte development | chordate embryonic development | cellular cation homeostasis | skeletal system morphogenesis | homeostatic process | embryo development ending in birth or egg hatching | iron ion homeostasis | embryonic morphogenesis | embryonic organ morphogenesis | regulation of growth | anatomical structure development | cofactor transport | embryonic skeletal system morphogenesis | developmental maturation | embryonic organ development | chemical homeostasis | heme transporter activity | animal organ development | ion homeostasis | cellular iron ion homeostasis | transmembrane transport | cell development | embryonic digit morphogenesis | regulation of developmental growth | anatomical structure morphogenesis | regulation of organ growth | regulation of developmental process | heme transport | developmental process | erythrocyte differentiation | cellular metal ion homeostasis | in utero embryonic development | transition metal ion homeostasis | skeletal system development | immune system process | body morphogenesis | hematopoietic or lymphoid organ development | circulatory system development | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | plasma membrane | mitochondrion | integral component of plasma membrane | membrane-bounded organelle | organelle | mitochondrial envelope | cell periphery | mitochondrial membrane | intracellular | membrane | intrinsic component of plasma membrane