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QuickView for FMO2 (gene)


Gene Symbol:
FMO2 Homo sapiens Homo sapiens
Full name:
flavin containing monooxygenase 2
Synonyms:
FMO1B1, dimethylaniline monooxygenase [N-oxide-forming] 2, FMO, pulmonary, dimethylaniline oxidase 2, flavin containing monooxygenase 2 (non-functional), pulmonary flavin-containing monooxygenase 2
Genomic Location:
Chr 1: 169421012-169448446
Description:
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1q24.3





GO Molecular Function

NADP binding | cofactor binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | anion binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | heterocyclic compound binding | oxidoreductase activity | N,N-dimethylaniline monooxygenase activity | small molecule binding

GO Biological Process

cellular process | toxin metabolic process | nucleotide metabolic process | xenobiotic metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | cellular response to xenobiotic stimulus | cellular nitrogen compound metabolic process | cofactor metabolic process | nitrogen compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | phosphorus metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | organophosphate metabolic process | small molecule metabolic process | NADPH oxidation | nucleobase-containing small molecule metabolic process | oxygen metabolic process | response to xenobiotic stimulus | phosphate-containing compound metabolic process | drug metabolic process | metabolic process | oxidation-reduction process | nucleobase-containing compound metabolic process | organic substance metabolic process | organic acid metabolic process | NADP metabolic process | nicotinamide nucleotide metabolic process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity | N,N-dimethylaniline monooxygenase activity

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane