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QuickView for FMO3 (gene)


Gene Symbol:
FMO3 Homo sapiens Homo sapiens
Full name:
flavin containing monooxygenase 3
Synonyms:
FMOII, TMAU, dJ127D3.1, dimethylaniline monooxygenase [N-oxide-forming] 3, FMO form 2, dimethylaniline oxidase 3, hepatic flavin-containing monooxygenase-3, trimethylamine monooxygenase
Genomic Location:
Chr 1: 169326660-169353583
Description:
Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and mult...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q24.3





GO Molecular Function

NADP binding | cofactor binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | anion binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | protein binding | trimethylamine monooxygenase activity | heterocyclic compound binding | oxidoreductase activity | N,N-dimethylaniline monooxygenase activity | small molecule binding

GO Biological Process

cellular process | xenobiotic metabolic process | response to stimulus | cellular response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | response to xenobiotic stimulus | trimethylamine monooxygenase activity | metabolic process | oxidation-reduction process | cellular metabolic process | oxidoreductase activity | N,N-dimethylaniline monooxygenase activity

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane