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QuickView for FOLR2;jsessionid=0A90E321004BAB6780431D62A248CD4A (gene)

Gene Symbol:
FOLR2 Homo sapiens Homo sapiens
Full name:
folate receptor beta
BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3, folate receptor beta, folate receptor 2 (fetal), folate receptor, fetal/placental, folate-binding protein, fetal/placental, placental folate-binding protein
Genomic Location:
Chr 11: 71605488-71610637
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68%...
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11

GO Molecular Function

modified amino acid binding | carboxylic acid binding | folic acid receptor activity | vitamin binding | anion binding | folic acid binding | amide binding | signaling receptor activity | ion binding | organic cyclic compound binding | drug binding | methotrexate binding | organic acid binding | heterocyclic compound binding | cargo receptor activity | small molecule binding

GO Biological Process

response to extracellular stimulus | response to nutrient levels | cell motility | establishment of localization | membrane fusion | defense response | cellular response to extracellular stimulus | response to drug | membrane organization | response to folic acid | cellular process | localization | dicarboxylic acid metabolic process | dicarboxylic acid transport | anion transport | folic acid transport | cell recognition | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular response to organonitrogen compound | folic acid receptor activity | cellular aromatic compound metabolic process | cellular component organization | folic acid-containing compound metabolic process | response to stimulus | response to stress | cellular response to vitamin | regulation of cell proliferation | sperm-egg recognition | reproduction | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | monocyte chemotaxis | cofactor metabolic process | pteridine-containing compound metabolic process | carboxylic acid transmembrane transport | cell chemotaxis | leukocyte migration | folate transmembrane transport | locomotion | response to nitrogen compound | cellular response to nutrient levels | nitrogen compound metabolic process | reproductive process | cell migration | cellular response to folic acid | vitamin transport | ion transmembrane transport | organic substance transport | cell-cell recognition | regulation of nitrogen compound metabolic process | small molecule metabolic process | vitamin transmembrane transport | cellular amide metabolic process | vesicle-mediated transport | response to nutrient | organic acid transport | folic acid metabolic process | fertilization | organic anion transport | cellular response to drug | cell communication | inflammatory response | regulation of protein metabolic process | leukocyte chemotaxis | positive regulation of cell proliferation | single fertilization | regulation of thymidylate synthase biosynthetic process | drug metabolic process | carboxylic acid metabolic process | multicellular organism reproduction | cellular response to nutrient | response to organic substance | vitamin metabolic process | import into cell | anion transmembrane transport | plasma membrane fusion | organic acid transmembrane transport | cofactor transport | metabolic process | fusion of sperm to egg plasma membrane involved in single fertilization | amide transport | endocytosis | cell adhesion | organic substance metabolic process | response to vitamin | folate import across plasma membrane | drug transport | transmembrane transport | response to organic cyclic compound | organic acid metabolic process | drug transmembrane transport | carboxylic acid transport | receptor-mediated endocytosis | response to organonitrogen compound | cellular modified amino acid metabolic process | heterocycle metabolic process | ion transport | cargo receptor activity | immune system process | cellular metabolic process | cellular response to organic substance | chemotaxis | sexual reproduction | mononuclear cell migration | multicellular organismal process

GO Cellular Component

intrinsic component of external side of plasma membrane | cell | intrinsic component of membrane | external side of plasma membrane | anchored component of plasma membrane | plasma membrane | anchored component of membrane | extracellular region | anchored component of external side of plasma membrane | cell periphery | cell surface | membrane | intrinsic component of plasma membrane