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QuickView for FOXN3;jsessionid=CB20C22AEE13CF49BFA2D147599A34BC (gene)


Gene Symbol:
FOXN3 Homo sapiens Homo sapiens
Full name:
forkhead box N3
Synonyms:
C14orf116, CHES1, PRO1635, forkhead box protein N3, checkpoint suppressor 1
Genomic Location:
Chr 14: 88692269-89155247
Description:
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is obse...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
FOXO1_02 POU6F1_01 GATTGGY_NFY_Q6_01 CACTGTG_MIR128A_MIR128B RTAAACA_FREAC2_01 SMTTTTGT_UNKNOWN AAGCCAT_MIR135A_MIR135B ETS_Q4 RYTTCCTG_ETS2_B NFY_C
Cytogenetic Map:
chr 14
14q31.3-q32.11


Transcripts Names
NM_001085471
NM_005197
Protein Names
O00409
A0A024R6I1
Q96II7
Q9UIE7



GO Molecular Function

RNA polymerase II transcription factor activity, sequence-specific DNA binding | protein binding | DNA-binding transcription factor activity | protein C-terminus binding

GO Biological Process

RNA metabolic process | regulation of cell cycle process | cranial skeletal system development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | bone development | cellular process | mitotic DNA integrity checkpoint | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | response to stimulus | regulation of mitotic cell cycle phase transition | response to stress | negative regulation of G2/M transition of mitotic cell cycle | craniofacial suture morphogenesis | cellular nitrogen compound biosynthetic process | mitotic G2 DNA damage checkpoint | regulation of cell cycle phase transition | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | regulation of cell cycle G2/M phase transition | system development | nitrogen compound metabolic process | negative regulation of mitotic cell cycle phase transition | mitotic DNA damage checkpoint | multicellular organism development | negative regulation of cell cycle G2/M phase transition | cellular response to DNA damage stimulus | regulation of gene expression | cellular response to stress | cell cycle | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | skeletal system morphogenesis | bone morphogenesis | regulation of RNA metabolic process | regulation of mitotic cell cycle | mitotic G2/M transition checkpoint | DNA-binding transcription factor activity | anatomical structure development | mitotic cell cycle | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | transcription, DNA-templated | negative regulation of cell cycle | regulation of transcription, DNA-templated | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | developmental process | heterocycle metabolic process | skeletal system development | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | DNA damage checkpoint | cell cycle checkpoint | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular