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QuickView for FOXO (gene)


Gene Symbol:
foxo D. melanogaster D. melanogaster
Full name:
forkhead box, sub-group O
Synonyms:
Afx, anon-WO0118547.374, cg3143, Dfoxo, DmelCG3143, Dmel_CG3143, DmQ95V5, FKHR, foxo, FOXO, Q95V55
Genomic Location:
Chr 3R: 9882674-9913698
Orthologs:
Danio rerio
External Links:
Entrez Gene





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

regulation of activin receptor signaling pathway | RNA metabolic process | transcription by RNA polymerase II | response to extracellular stimulus | cell morphogenesis | regulation of cell cycle process | myoblast fusion | negative regulation of cellular response to insulin stimulus | positive regulation of macromolecule biosynthetic process | response to nutrient levels | positive regulation of behavior | neuron projection morphogenesis | regulation of localization | entry into diapause | syncytium formation by plasma membrane fusion | regulation of hemocyte proliferation | microtubule bundle formation | positive regulation of lipid catabolic process | eye development | regulation of autophagy | regulation of immune system process | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | microtubule cytoskeleton organization | cell differentiation | nervous system development | cellular response to extracellular stimulus | generation of precursor metabolites and energy | cell part morphogenesis | neurogenesis | glucose homeostasis | generation of neurons | microtubule-based process | sterol metabolic process | positive regulation of cellular biosynthetic process | cellular process | cell projection morphogenesis | negative regulation of signaling | neuron development | negative regulation of developmental growth | negative regulation of nucleic acid-templated transcription | stem cell population maintenance | cellular response to starvation | regulation of cell cycle | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | response to peptide hormone | regulation of behavior | muscle structure development | muscle cell differentiation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | steroid biosynthetic process | cellular component organization | response to stimulus | cell morphogenesis involved in neuron differentiation | regulation of feeding behavior | response to stress | cellular polysaccharide metabolic process | positive regulation of feeding behavior | cellular nitrogen compound biosynthetic process | alcohol metabolic process | regulation of cell proliferation | polysaccharide metabolic process | response to peptide | circadian rhythm | response to starvation | ecdysone biosynthetic process | rhythmic process | cellular nitrogen compound metabolic process | instar larval or pupal development | regulation of macroautophagy | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | regulation of cellular component size | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of triglyceride metabolic process | regulation of lipid storage | regulation of nucleic acid-templated transcription | female germ-line stem cell population maintenance | organic hydroxy compound metabolic process | response to nitrogen compound | cellular response to hormone stimulus | response to external biotic stimulus | system development | cellular response to nutrient levels | glycogen metabolic process | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of growth | multicellular organism development | syncytium formation | cellular response to peptide hormone stimulus | hormone biosynthetic process | cellular response to insulin stimulus | lipid metabolic process | cellular response to oxidative stress | regulation of hormone levels | cellular response to amino acid starvation | positive regulation of cell cycle | regulation of gene expression | rhythmic behavior | cellular response to stress | cellular response to peptide | insulin receptor signaling pathway | regulation of cell cycle arrest | positive regulation of cellular metabolic process | negative regulation of lipid storage | animal organ morphogenesis | sterol biosynthetic process | regulation of nitrogen compound metabolic process | regulation of Notch signaling pathway | enzyme linked receptor protein signaling pathway | small molecule metabolic process | negative regulation of insulin receptor signaling pathway | cellular carbohydrate metabolic process | regulation of transcription by RNA polymerase II | response to oxidative stress | ecdysteroid metabolic process | cellular ketone metabolic process | biosynthetic process | locomotory behavior | aromatic compound biosynthetic process | lipid biosynthetic process | negative regulation of multicellular organism growth | carbohydrate metabolic process | compound eye morphogenesis | cell morphogenesis involved in differentiation | post-embryonic development | sensory organ development | response to bacterium | compound eye development | cell communication | regulation of cellular metabolic process | eye morphogenesis | regulation of lipid catabolic process | positive regulation of signal transduction | homeostatic process | regulation of RNA metabolic process | striated muscle cell differentiation | negative regulation of cell growth | dormancy process | positive regulation of cell cycle arrest | neuron differentiation | positive regulation of triglyceride metabolic process | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regulation of growth | response to organic substance | negative regulation of fat cell proliferation | response to insulin | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | somatic muscle development | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of transcription, DNA-templated | negative regulation of cell size | chemical homeostasis | behavior | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | neuron projection development | organic substance metabolic process | maintenance of cell number | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | entry into reproductive diapause | regulation of insulin receptor signaling pathway | gene expression | positive regulation of G-protein coupled receptor protein signaling pathway | regulation of cellular response to insulin stimulus | ecdysone metabolic process | cytoskeleton organization | transcription, DNA-templated | dendrite morphogenesis | anatomical structure formation involved in morphogenesis | steroid metabolic process | multicellular organism aging | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | myotube differentiation | cell development | energy reserve metabolic process | regulation of developmental growth | determination of adult lifespan | regulation of cell size | hormone metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of triglyceride catabolic process | regulation of organ growth | response to biotic stimulus | ecdysteroid biosynthetic process | dendrite development | regulation of developmental process | regulation of G-protein coupled receptor protein signaling pathway | energy derivation by oxidation of organic compounds | developmental process | organelle organization | cellular glucan metabolic process | positive regulation of cell cycle process | regulation of cell growth | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | germ-line stem cell population maintenance | circadian behavior | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | response to amino acid starvation | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | locomotor rhythm | negative regulation of Notch signaling pathway | cellular metabolic process | cellular response to organic substance | aging | carbohydrate homeostasis | regulation of cellular component organization | positive regulation of octopamine signaling pathway | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular