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QuickView for FPR1 (gene)


Gene Symbol:
FPR1 Homo sapiens Homo sapiens
Full name:
formyl peptide receptor 1
Synonyms:
FMLP, FPR, fMet-Leu-Phe receptor, N-formylpeptide chemoattractant receptor, fMLP receptor
Genomic Location:
Chr 19: 56940838-56946962
Description:
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19q13.41


Transcripts Names
NM_002029
NM_001193306
Protein Names
Q9NS48
Q86U52
Q14939
P21462
Q7Z6A4



GO Molecular Function

transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor binding | N-formyl peptide receptor activity | signaling receptor activity | scavenger receptor binding | protein binding | peptide receptor activity | G-protein coupled peptide receptor activity | RAGE receptor binding

GO Biological Process

positive regulation of immune response | exocytosis | response to cytokine | immune response-regulating signaling pathway | neutrophil activation | intracellular signal transduction | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | regulation of MAP kinase activity | immune response-activating cell surface receptor signaling pathway | defense response | cellular chemical homeostasis | positive regulation of phosphate metabolic process | cellular process | secretion | leukocyte degranulation | localization | cellular homeostasis | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | calcium ion homeostasis | G-protein coupled receptor activity | response to stimulus | neutrophil degranulation | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | leukocyte activation involved in immune response | secretion by cell | immune response-activating signal transduction | G-protein coupled receptor signaling pathway | positive regulation of protein serine/threonine kinase activity | activation of protein kinase activity | metal ion homeostasis | locomotion | regulation of signal transduction | regulation of MAPK cascade | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | N-formyl peptide receptor activity | leukocyte mediated immunity | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | nitric oxide mediated signal transduction | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | vesicle-mediated transport | second-messenger-mediated signaling | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | regulated exocytosis | cation homeostasis | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | inflammatory response | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | neutrophil activation involved in immune response | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | complement receptor mediated signaling pathway | positive regulation of molecular function | activation of MAPK activity | activation of immune response | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | regulation of intracellular signal transduction | cell surface receptor signaling pathway | chemical homeostasis | immune response | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | phospholipase C-activating G-protein coupled receptor signaling pathway | cell activation | positive regulation of MAPK cascade | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | G-protein coupled peptide receptor activity | positive regulation of phosphorylation | positive regulation of MAP kinase activity | neutrophil mediated immunity | cellular metal ion homeostasis | positive regulation of metabolic process | immune system process | cellular response to organic substance | chemotaxis | divalent inorganic cation homeostasis | positive regulation of signaling | signal transduction | regulation of signaling | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | tertiary granule | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | secretory granule membrane | ficolin-1-rich granule membrane | secretory vesicle | endomembrane system | plasma membrane | azurophil granule membrane | vacuole | vesicle | lytic vacuole | membrane-bounded organelle | organelle | vesicle membrane | lysosome | cell periphery | azurophil granule | intracellular vesicle | intracellular | lysosomal membrane | membrane | cytoplasmic vesicle membrane | vacuolar membrane