QuickView for FSHR (gene)
- Gene Symbol:
- FSHR
Homo sapiens - Full name:
- follicle stimulating hormone receptor
- Synonyms:
- FSHR1, FSHRO, LGR1, ODG1, follicle-stimulating hormone receptor, FSH receptor, follitropin receptor
- Genomic Location:
- Chr 2: 49043156-49235134
- Description:
-
The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
2p16.3
| Transcripts Names |
|---|
| NM_000145 |
| NM_181446 |
| XM_011532736 |
| XM_011532740 |
| XM_011532735 |
| XM_011532734 |
| XM_011532733 |
GO Molecular Function
transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity | protein binding | follicle-stimulating hormone receptor activity | peptide receptor activity | G-protein coupled peptide receptor activity | protein-hormone receptor activity
GO Biological Process
positive regulation of cyclase activity | regulation of ERK1 and ERK2 cascade | developmental process involved in reproduction | positive regulation of lyase activity | intracellular signal transduction | ovarian follicle development | gonad development | female gonad development | response to hormone | male gamete generation | positive regulation of phosphate metabolic process | hormone-mediated signaling pathway | cellular process | reproductive system development | multicellular organismal reproductive process | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | gamete generation | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | development of primary sexual characteristics | G-protein coupled receptor activity | response to stimulus | female gamete generation | positive regulation of protein metabolic process | positive regulation of phosphatidylinositol 3-kinase signaling | ovulation cycle | development of primary female sexual characteristics | reproduction | rhythmic process | G-protein coupled receptor signaling pathway | cellular response to hormone stimulus | system development | reproductive process | regulation of signal transduction | multicellular organism development | regulation of MAPK cascade | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | response to follicle-stimulating hormone | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of phosphorylation | cellular response to gonadotropin stimulus | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | second-messenger-mediated signaling | positive regulation of adenylate cyclase activity | regulation of cellular protein metabolic process | regulation of cyclase activity | ovulation cycle process | cell communication | regulation of cellular metabolic process | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | positive regulation of molecular function | multicellular organism reproduction | activation of adenylate cyclase activity | development of primary male sexual characteristics | positive regulation of protein modification process | response to organic substance | follicle-stimulating hormone signaling pathway | cAMP-mediated signaling | male sex differentiation | regulation of intracellular signal transduction | anatomical structure development | follicle-stimulating hormone receptor activity | male gonad development | animal organ development | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | response to gonadotropin | positive regulation of MAPK cascade | cellular response to follicle-stimulating hormone stimulus | regulation of adenylate cyclase activity | regulation of protein kinase A signaling | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | G-protein coupled peptide receptor activity | positive regulation of phosphorylation | reproductive structure development | developmental process | spermatogenesis | positive regulation of metabolic process | female sex differentiation | cellular response to organic substance | sex differentiation | sexual reproduction | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | cell periphery | intracellular | membrane | intrinsic component of plasma membrane
