QuickView for FTO;jsessionid=41EC3861CF9232A1A0F79EBA027E5B4F (gene)

Gene Symbol:

FTO Homo sapiens

Full name:

FTO, alpha-ketoglutarate dependent dioxygenase

Synonyms:

ALKBH9, BMIQ14, GDFD, alpha-ketoglutarate-dependent dioxygenase FTO, AlkB homolog 9, fat mass and obesity associated, fat mass and obesity-associated protein

Genomic Location:

Chr 16: 52295376-52705882

Description:

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiov...

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This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

16q12.2

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