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QuickView for FUT6;jsessionid=7036D412F3EE2C5A7A9B46FA235E2E9C (gene)


Gene Symbol:
FUT6 Homo sapiens Homo sapiens
Full name:
fucosyltransferase 6
Synonyms:
FCT3A, FT1A, Fuc-TVI, FucT-VI, alpha-(1,3)-fucosyltransferase 6, fucosyltransferase 6 (alpha (1,3) fucosyltransferase), fucosyltransferase VI, galactoside 3-L-fucosyltransferase
Genomic Location:
Chr 19: 5781637-5790742
Description:
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene.
Orthologs:
Macaca mulatta Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19p13.3





GO Molecular Function

3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity | catalytic activity | fucosyltransferase activity | transferase activity, transferring glycosyl groups | alpha-(1->3)-fucosyltransferase activity | transferase activity, transferring hexosyl groups | transferase activity

GO Biological Process

cellular process | organic substance catabolic process | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity | sphingolipid metabolic process | carbohydrate catabolic process | glycoprotein biosynthetic process | catabolic process | cellular lipid metabolic process | fucosylation | ceramide metabolic process | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | protein modification process | macromolecule glycosylation | cellular biosynthetic process | macromolecule modification | nitrogen compound metabolic process | fucosyltransferase activity | lipid metabolic process | fucose metabolic process | monosaccharide metabolic process | small molecule metabolic process | cellular amide metabolic process | biosynthetic process | carbohydrate metabolic process | alpha-(1->3)-fucosyltransferase activity | protein metabolic process | metabolic process | membrane lipid metabolic process | hexose metabolic process | organic substance metabolic process | L-fucose catabolic process | cellular protein metabolic process | cellular macromolecule biosynthetic process | cellular protein modification process | carbohydrate derivative metabolic process | protein glycosylation | glycosylation | cellular metabolic process | glycoprotein metabolic process | macromolecule metabolic process

GO Cellular Component

integral component of membrane | Golgi stack | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | Golgi apparatus | Golgi cisterna | endomembrane system | vesicle | extracellular exosome | Golgi cisterna membrane | Golgi membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | intracellular | membrane