QuickView for FXR2;jsessionid=025EF5FECEE11645C1A2480A8FD1E277 (gene)

Gene Symbol:

FXR2 Homo sapiens

Full name:

FMR1 autosomal homolog 2

Synonyms:

FMR1L2, FXR2P, fragile X mental retardation syndrome-related protein 2, fragile X mental retardation, autosomal homolog 2, fragile X-mental retardation 1-like 2

Genomic Location:

Chr 17: 7435272-7458796

Description:

The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitiv...

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The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  CACTGTG_MIR128A_MIR128B ,  SP1_01 ,  MAZR_01 ,  ZF5_01 ,  NFY_C ,  CTCNANGTGNY_UNKNOWN ,  MYCMAX_B ,  GGGAGGRR_MAZ_Q6 ,  GGTGTGT_MIR329 ,  CACCCBINDINGFACTOR_Q6 ,  E2F1_Q6_01 ,  TGCGCANK_UNKNOWN ,  SP3_Q3 ,  CAGGGTC_MIR504 ,  GGGCGGR_SP1_Q6 ,  TAGAACC_MIR182 ,  E4F1_Q6 ,  E2F1_Q3_01 ,  AP2_Q3 ,  NRF1_Q6 ,  GTGCCTT_MIR506 ,  AP2_Q6 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CCAGGGG_MIR331 ,  CREB_Q2 ,  PAX5_01 ,  CTTTGT_LEF1_Q2 ,  RCGCANGCGY_NRF1_Q6 ,  ACAGGGT_MIR10A_MIR10B ,  GGCKCATGS_UNKNOWN ,  MYB_Q3 ,  OLF1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-10 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-331 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-504

Cytogenetic Map:

17p13.1

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