QuickView for Foxp1 (gene)

Gene Symbol:

FOXP1 Homo sapiens

Full name:

forkhead box P1

Synonyms:

12CC4, HSPC215, MFH, QRF1, hFKH1B, forkhead box protein P1, fork head-related protein like B, glutamine-rich factor 1, mac-1-regulated forkhead

Genomic Location:

Chr 3: 71087426-71715830

Description:

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gen...

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This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  POU6F1_01 ,  PAX4_04 ,  ACTGTAG_MIR139 ,  CACTGCC_MIR34A_MIR34C_MIR449 ,  GTGCCAT_MIR183 ,  TTTGCAC_MIR19A_MIR19B ,  SMTTTTGT_UNKNOWN ,  HNF3ALPHA_Q6 ,  GATA1_03 ,  OCT1_B ,  TAL1ALPHAE47_01 ,  ETS_Q4 ,  TTANTCA_UNKNOWN ,  TCANNTGAY_SREBP1_01 ,  FOXJ2_02 ,  RYTTCCTG_ETS2_B ,  OCT1_04 ,  RSRFC4_01 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  NFAT_Q6 ,  OCT1_01 ,  HEN1_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  SYATTGTG_UNKNOWN ,  YTATTTTNR_MEF2_02 ,  SRF_Q6 ,  SMAD3_Q6 ,  TTCNRGNNNNTTC_HSF_Q6 ,  CTACTGT_MIR199A ,  TTCCGTT_MIR191 ,  AAANWWTGC_UNKNOWN ,  LXR_DR4_Q3 ,  CEBP_Q2_01 ,  CAGTGTT_MIR141_MIR200A ,  FAC1_01 ,  ZIC3_01 ,  TTTNNANAGCYR_UNKNOWN ,  NKX22_01 ,  CTAWWWATA_RSRFC4_Q2 ,  GCCATNTTG_YY1_Q6 ,  OCT1_Q5_01 ,  TAAWWATAG_RSRFC4_Q2 ,  CTTTGTA_MIR524 ,  MEF2_02 ,  TATAAA_TATA_01 ,  CEBP_Q2 ,  CEBPDELTA_Q6 ,  CEBPB_01 ,  TAL1BETAE47_01 ,  GGGGCCC_MIR296 ,  PAX4_02 ,  ACATTCC_MIR1_MIR206 ,  TTGGGAG_MIR150 ,  TITF1_Q3 ,  CAGGTA_AREB6_01 ,  RP58_01 ,  CEBP_01 ,  CDX2_Q5 ,  AP4_01 ,  TATA_C ,  SP3_Q3 ,  ZID_01 ,  ACCAAAG_MIR9 ,  ATGTTAA_MIR302C ,  CEBPB_02 ,  SRF_Q4 ,  ACTGCCT_MIR34B ,  GATA6_01 ,  S8_01 ,  MGGAAGTG_GABP_B ,  ACTGAAA_MIR30A3P_MIR30E3P ,  E47_01 ,  ACTGCAG_MIR173P ,  TGTTTGY_HNF3_Q6 ,  OCT1_06 ,  RNGTGGGC_UNKNOWN ,  HMGIY_Q6 ,  HLF_01 ,  OCT1_02 ,  GGCAGCT_MIR22 ,  POU3F2_02 ,  AACATTC_MIR4093P ,  TTGTTT_FOXO4_01 ,  ATF1_Q6 ,  CEBP_C ,  AFP1_Q6 ,  MSX1_01 ,  RTTTNNNYTGGM_UNKNOWN ,  MEF2_03 ,  WTTGKCTG_UNKNOWN ,  TEF_Q6 ,  IK1_01 ,  ZIC2_01 ,  CTGCAGY_UNKNOWN ,  TAL1BETAITF2_01 ,  SRF_Q5_01 ,  CTTTGT_LEF1_Q2 ,  CAGCTG_AP4_Q5 ,  CDC5_01 ,  P300_01 ,  MZF1_02 ,  TTANWNANTGGM_UNKNOWN ,  DR4_Q2 ,  ETS1_B ,  ACCATTT_MIR522 ,  SRF_C ,  TATTATA_MIR374 ,  TCF11MAFG_01 ,  STAT5A_02 ,  MYB_Q3 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-150 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-191 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-221 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-324-3p ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-33 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-34b ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-409-3p ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

3p13

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